• International consensus recommendations for the identification and treatment of tuberous sclerosis complex-associated neuropsychiatric disorders (TAND)

  

  Author: de Vries, Petrus J. ; Heunis, Tosca-Marie ; Vanclooster, Stephanie ; Chambers, Nola ; Bissell, Stacey ; Byars, Anna W. ; Flinn, Jennifer ; Gipson, Tanjala T. ; van Eeghen, Agnies M. ; Waltereit, Robert ; Capal, Jamie K. ; Cukier, Sebastián ; Davis, Peter E. ; Smith, Catherine ; Kingswood, J. C. ; Schoeters, Eva ; Srivastava, Shoba ; Takei, Megumi ; Gardner-Lubbe, Sugnet ; Kumm, Aubrey J. ; Krueger, Darcy A. ; Sahin, Mustafa ; De Waele, Liesbeth ; Jansen, Anna C. Date: 14 Sep 2023 Background Tuberous sclerosis complex (TSC) is associated with a wide range of physical manifestations for which international clinical recommendations for diagnosis and management have been established. TSC is, however, also associated with ... Read more c b
• A multicentre neonatal interventional randomised controlled trial of nebulized surfactant for preterm infants with respiratory distress: Neo-INSPIRe trial protocol

  

  Author: Lategan, Ilse ; Durand, David ; Harrison, Michael ; Nakwa, Firdose ; Van Wyk, Lizelle ; Velaphi, Sithembiso ; Horn, Alan ; Kali, Gugu ; Soll, Roger ; Ehret, Danielle ; Zar, Heather ; Tooke, Lloyd Date: 19 Sep 2023 Introduction Respiratory distress syndrome in preterm infants is an important cause of morbidity and mortality. Less invasive methods of surfactant administration, along with the use of continuous positive airway pressure (CPAP), have improved ... Read more c b
• Optimising engagement in a digital parenting intervention to prevent violence against adolescents in Tanzania: protocol for a cluster randomised factorial trial

  

  Author: Janowski, Roselinde ; Green, Ohad ; Shenderovich, Yulia ; Stern, David ; Clements, Lily ; Wamoyi, Joyce ; Wambura, Mwita ; Lachman, Jamie M. ; Melendez-Torres, G. J. ; Gardner, Frances ; Baerecke, Lauren ; Te Winkel, Esmee ; Booij, Anna ; Setton, Orli ; Tsoanyane, Sibongile ; Mjwara, Sussie ; Christine, Laetitia ; Ornellas, Abigail ; Chetty, Nicole ; Klapwijk, Jonathan ; Awah, Isang ; Manjengenja, Nyasha ; Sokoine, Kudely ; Majikata, Sabrina ; Cluver, Lucie D. Date: 23 Jun 2023 Background Violence against adolescents is a universal reality, with severe individual and societal costs. There is a critical need for scalable and effective violence prevention strategies such as parenting programmes, particularly in low- ... Read more c b
• Post-trial access to and use of pre-exposure prophylaxis in Durban, South Africa

  

  Author: Beesham, Ivana ; Milford, Cecilia ; Smit, Jenni ; Joseph Davey, Dvora L. ; Baeten, Jared M. ; Heffron, Renee ; Beksinska, Mags ; Mansoor, Leila E. Date: 22 Jun 2023 Background HIV endpoint-driven clinical trials increasingly provide oral pre-exposure prophylaxis (PrEP) as standard of prevention during the trial, however, among participants desiring to continue using PrEP at trial exit, little is known ... Read more c b
• How South Africa Used National Cycle Threshold (Ct) Values to Continuously Monitor SARS-CoV-2 Laboratory Test Quality

  

  Author: Scott, Lesley Erica ; Hsiao, Nei-yuan ; Dor, Graeme ; Hans, Lucia ; Marokane, Puleng ; da Silva, Manuel Pedro ; Preiser, Wolfgang ; Vreede, Helena ; Tsoka, Jonathan ; Mlisana, Koleka ; Stevens, Wendy Susan Date: 01 Aug 2023 The high demand for SARS-CoV-2 tests but limited supply to South African laboratories early in the COVID-19 pandemic resulted in a heterogenous diagnostic footprint of open and closed molecular testing platforms being implemented. Ongoing ... Read more c b
• Correlates of COVID-19 vaccination intentions and opinions about mandates among four groups of adults in South Africa with distinct vaccine intentions: evidence from a large national survey

  

  Author: Eyal, Katherine ; Njozela, Lindokuhle ; Köhler, Timothy ; Ingle, Kim ; Brophy, Timothy ; Buttenheim, Alison ; Maughan-Brown, Brendan Date: 11 Sep 2023 Abstract Introduction Despite a high number of recorded COVID-19 infections and deaths in South Africa, COVID-19 vaccine coverage remained low in March 2022, ten months into the national vaccine ... Read more c b
• Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa

  

  Author: Singh, Y. ; Castillo-Mancilla, J. ; Madimabe, R. ; Jennings, L. ; Ferraris, C. M. ; Robbins, R. N. ; Anderson, P. L. ; Remien, R. H. ; Orrell, C. Date: 14 Sep 2023 Background Suboptimal antiretroviral (ART) adherence can lead to virologic failure with consequent HIV-1 resistance. Tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) is a powerful biomarker of cumulative adherence, predictive of ... Read more c b
• On the Fence: The Impact of Education on Support for Electric Fencing to Prevent Conflict between Humans and Baboons in Kommetjie, South Africa

  

  Author: Walsh, Debbie ; O’Riain, M. Justin ; Nattrass, Nicoli ; Gaynor, David Date: 27 Jun 2023 Few studies test whether education can help increase support for wildlife management interventions. This mixed methods study sought to test the importance of educating a community on the use of a baboon-proof electric fence to mitigate negative ... Read more c b
• Anticipated benefits and challenges of implementing group care in Suriname’s maternity and child care sector: a contextual analysis

  

  Author: Martens, Nele ; Hindori-Mohangoo, Ashna D. ; Hindori, Manodj P. ; Damme, Astrid V. ; Beeckman, Katrien ; Reis, Ria ; Crone, Mathilde R. ; van der Kleij, Rianne R. Date: 18 Aug 2023 Background Suriname is a uppermiddle-income country with a relatively high prevalence of preventable pregnancy complications. Access to and usage of high-quality maternity care services are lacking. The implementation of group care (GC) may ... Read more c b
• Salts of S-(+)-Ibuprofen Formed via Its Reaction with the Antifibrinolytic Agents Aminocaproic Acid and Tranexamic Acid: Synthesis and Characterization

  

  Author: Frösler, Hannah M. ; Ramulumo, Humbelani S. ; Edmonds-Smith, Cesarina ; Caira, Mino R. Date: 08 Aug 2023 The paucity of multi-component compounds containing the non-steroidal anti-inflammatory drug (NSAID) S-(+)-ibuprofen (S-IBU) in combination with other drugs prompted the present study, which describes 1:1 salts of this active pharmaceutical ... Read more c b
• Investigation on the Effect of Mesomixing on Crystal Quality during Antisolvent Crystallization of Nd2(SO4)3·8H2O

  

  Author: Baloyi, Tinjombo Octavious ; Chivavava, Jemitias ; Lewis, Alison Emslie Date: 31 Jul 2023 Rare earth elements (REEs) are essential for permanent magnets that are vital for wind turbines and electric vehicles motors (EV), and are also used in a range of high-tech devices such as smartphones, digital cameras, and electronic displays. ... Read more c b
• Biodefoamer-Supported Activated Sludge System for the Treatment of Poultry Slaughterhouse Wastewater

  

  Author: Dlangamandla, Cynthia ; Ntwampe, Seteno K. O. ; Basitere, Moses ; Chidi, Boredi S. ; Okeleye, Benjamin I. Date: 14 Aug 2023 Poultry slaughterhouse wastewater (PSW) is laden with fats, oil, and grease (FOG), as well as proteins. As such, PSW promotes the proliferation of filamentous organisms, which cause foam formation. In this study, the production of biological ... Read more c b
• A Global Systematic Review of Improving Crop Model Estimations by Assimilating Remote Sensing Data: Implications for Small-Scale Agricultural Systems

  

  Author: Dlamini, Luleka ; Crespo, Olivier ; van Dam, Jos ; Kooistra, Lammert Date: 17 Aug 2023 There is a growing effort to use access to remote sensing data (RS) in conjunction with crop model simulation capability to improve the accuracy of crop growth and yield estimates. This is critical for sustainable agricultural management and ... Read more c b
• Associations between prenatal alcohol and tobacco exposure on Doppler flow velocity waveforms in pregnancy: a South African study

  

  Author: Jonker, Deborah ; Melly, Brigitte ; Brink, Lucy T. ; Odendaal, Hein J. ; Stein, Dan J. ; Donald, Kirsten A. Date: 23 Aug 2023 Background The negative impact of prenatal alcohol and tobacco exposure (PAE and PTE) on fetal development and birth outcomes are well described, yet pathophysiologic mechanisms are less clear. Our aim was to investigate (1) the associations ... Read more c b
• Identification and characterization of a polyomavirus in the thornback skate (Raja clavata)

  

  Author: Abrantes, Joana ; Varsani, Arvind ; Pereira, Paulo ; Maia, Catarina ; Farias, Inês ; Veríssimo, Ana ; Neves, Fabiana Date: 24 Aug 2023 Abstract Members of the family Polyomaviridae have a circular double-stranded DNA genome that have been identified in various hosts ranging from mammals to arachnids. Here we report the identification and analysis of a complete ... Read more c b
• Eliminating Vertical Transmission of HIV in South Africa: Establishing a Baseline for the Global Alliance to End AIDS in Children

  

  Author: Haeri Mazanderani, Ahmad F. ; Murray, Tanya Y. ; Johnson, Leigh F. ; Ntloana, Mathilda ; Silere-Maqetseba, Tabisa ; Guo, Sufang ; Sherman, Gayle G. Date: 01 Aug 2023 To gain a detailed overview of vertical transmission in South Africa, we describe insights from the triangulation of data sources used to monitor the national HIV program. HIV PCR results from the National Health Laboratory Service (NHLS) ... Read more c b
• Understanding the impact of tuberous sclerosis complex: development and validation of the TSC-PROM

  

  Author: Müller, Annelieke R. ; Luijten, Michiel A. J. ; Haverman, Lotte ; de Ranitz-Greven, Wendela L. ; Janssens, Peter ; Rietman, André B. ; ten Hoopen, Leontine W. ; de Graaff, Laura C. G. ; de Wit, Marie-Claire ; Jansen, Anna C. ; Gipson, Tanjala ; Capal, Jamie K. ; de Vries, Petrus J. ; van Eeghen, Agnies M. Date: 08 Aug 2023 Background Tuberous sclerosis complex (TSC) is a rare and complex genetic disorder, associated with tumor growth in various organ systems, epilepsy, and a range of neuropsychiatric manifestations including intellectual disability. With ... Read more c b
• Antisense Therapy for Infectious Diseases

  

  Author: Buthelezi, Lwanda Abonga ; Pillay, Shandre ; Ntuli, Noxolo Nokukhanya ; Gcanga, Lorna ; Guler, Reto Date: 21 Aug 2023 Infectious diseases, particularly Tuberculosis (TB) caused by Mycobacterium tuberculosis, pose a significant global health challenge, with 1.6 million reported deaths in 2021, making it the most fatal disease caused by a single infectious ... Read more c b
• The Impact of Co-Infections for Human Gammaherpesvirus Infection and Associated Pathologies

  

  Author: Chinna, Prishanta ; Bratl, Katrin ; Lambarey, Humaira ; Blumenthal, Melissa J. ; Schäfer, Georgia Date: 22 Aug 2023 The two oncogenic human gammaherpesviruses Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV) cause significant disease burden, particularly in immunosuppressed individuals. Both viruses display latent and lytic ... Read more c b
• Incidence of catastrophic health spending in Indonesia: insights from a Household Panel Study 2018–2019

  

  Author: Fattah, Rifqi A. ; Cheng, Qinglu ; Thabrany, Hasbullah ; Susilo, Dwidjo ; Satrya, Aryana ; Haemmerli, Manon ; Kosen, Soewarta ; Novitasari, Danty ; Puteri, Gemala C. ; Adawiyah, Eviati ; Hayen, Andrew ; Gilson, Lucy ; Mills, Anne ; Tangcharoensathien, Viroj ; Jan, Stephen ; Asante, Augustine ; Wiseman, Virginia Date: 06 Sep 2023 Background Indonesia implemented one of the world’s largest single-payer national health insurance schemes (the Jaminan Kesehatan Nasional or JKN) in 2014. This study aims to assess the incidence of catastrophic health spending (CHS) and its ... Read more c b

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