Donor milk intake and infant growth in a South African neonatal unit: a cohort study

 

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dc.contributor.author Sparks, Hayley
dc.contributor.author Linley, Lucy
dc.contributor.author Beaumont, Jennifer L
dc.contributor.author Robinson, Daniel T
dc.date.accessioned 2018-09-10T07:22:33Z
dc.date.available 2018-09-10T07:22:33Z
dc.date.issued 2018-09-04
dc.identifier.citation Sparks, H., Linley, L., Beaumont, J. L., & Robinson, D. T. (2018). Donor milk intake and infant growth in a South African neonatal unit: a cohort study. International Breastfeeding Journal, 13(1), 41.
dc.identifier.uri https://doi.org/10.1186/s13006-018-0183-8
dc.identifier.uri http://hdl.handle.net/11427/28446
dc.description.abstract Background Implications of donor milk feedings on infant growth in resource limited settings remain uncertain. This knowledge gap includes the impact of donor milk availability on infant intake of mother’s own milk. Therefore, this investigation aimed to measure intake and growth in infants receiving donor milk when born to women from resource limited backgrounds with high rates of human immunodeficiency virus (HIV). Methods A retrospective cohort study enrolled eligible infants admitted to a South African combined neonatal intensive and secondary high care unit, within a one year admission period during 2015, with signed consent for donor milk feedings. A certified milk bank provided donor milk. Daily nutritional intake during the first month was recorded. Details included proportional intake of donor milk, mother’s own milk and infant formula. The primary outcome of infant growth velocity from day back to birth weight to discharge was calculated when length of stay was ≥14 days. Analyses primarily used T-tests; mixed effects models compared weekly calorie intake. Results One hundred five infants with donor milk consent were born at 30.9 ± 3.6 weeks of gestation, weighing 1389 ± 708 g. Forty percent of mothers had HIV. Infant growth velocity did not differ based on percent of feedings as donor milk (≥ 50%: 11.8 ± 4.9 g/kg/d; < 50%: 13.5 ± 5.3 g/kg/d; p = 0.3). Percent of feedings from donor milk was similar based on maternal HIV status (positive: 31 ± 25%; negative: 36 ± 29%; p = 0.4), as was percent of feedings as mother’s milk (positive: 53 ± 35%; negative: 58 ± 30%; p = 0.4). Calorie intake increased markedly during the first two weeks and then plateaued (p < 0.0001). Conclusions Donor milk feedings in higher proportions did not further impair growth of infants managed in a South African combined neonatal intensive and secondary high care unit with growth rates already below reference ranges. The provision of donor milk contributed to feedings being composed of primarily human milk during the first month. Increasing early calorie intake may improve infant growth in this center.
dc.language.iso en
dc.publisher BioMed Central
dc.source International Breastfeeding Journal
dc.source.uri https://internationalbreastfeedingjournal.biomedcentral.com/
dc.subject.other Milk bank
dc.subject.other Human milk
dc.subject.other Donor milk
dc.subject.other Infant growth
dc.subject.other Very low birth weight
dc.subject.other Premature infant
dc.title Donor milk intake and infant growth in a South African neonatal unit: a cohort study
dc.type Journal Article
dc.date.updated 2018-09-09T03:20:44Z
dc.rights.holder The Author(s).
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Division of Neonatology en_ZA
uct.type.filetype Text
uct.type.filetype Image


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