Impact of district mental health care plans on symptom severity and functioning of patients with priority mental health conditions: the Programme for Improving Mental Health Care (PRIME) cohort protocol

 

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dc.contributor.author Baron, Emily C
dc.contributor.author Rathod, Sujit D
dc.contributor.author Hanlon, Charlotte
dc.contributor.author Prince, Martin
dc.contributor.author Fedaku, Abebaw
dc.contributor.author Kigozi, Fred
dc.contributor.author Jordans, Mark
dc.contributor.author Luitel, Nagendra P
dc.contributor.author Medhin, Girmay
dc.contributor.author Murhar, Vaibhav
dc.contributor.author Nakku, Juliet
dc.contributor.author Patel, Vikram
dc.contributor.author Petersen, Inge
dc.contributor.author Selohilwe, One
dc.contributor.author Shidhaye, Rahul
dc.contributor.author Ssebunnya, Joshua
dc.contributor.author Tomlinson, Mark
dc.contributor.author Lund, Crick
dc.contributor.author De Silva, Mary
dc.date.accessioned 2018-05-04T07:46:26Z
dc.date.available 2018-05-04T07:46:26Z
dc.date.issued 2018-03-06
dc.identifier.citation BMC Psychiatry. 2018 Mar 06;18(1):61
dc.identifier.uri http://dx.doi.org/10.1186/s12888-018-1642-x
dc.identifier.uri http://hdl.handle.net/11427/27927
dc.description.abstract Background The Programme for Improving Mental Health Care (PRIME) sought to implement mental health care plans (MHCP) for four priority mental disorders (depression, alcohol use disorder, psychosis and epilepsy) into routine primary care in five low- and middle-income country districts. The impact of the MHCPs on disability was evaluated through establishment of priority disorder treatment cohorts. This paper describes the methodology of these PRIME cohorts. Methods One cohort for each disorder was recruited across some or all five districts: Sodo (Ethiopia), Sehore (India), Chitwan (Nepal), Dr. Kenneth Kaunda (South Africa) and Kamuli (Uganda), comprising 17 treatment cohorts in total (N = 2182). Participants were adults residing in the districts who were eligible to receive mental health treatment according to primary health care staff, trained by PRIME facilitators as per the district MHCP. Patients who screened positive for depression or AUD and who were not given a diagnosis by their clinicians (N = 709) were also recruited into comparison cohorts in Ethiopia, India, Nepal and South Africa. Caregivers of patients with epilepsy or psychosis were also recruited (N = 953), together with or on behalf of the person with a mental disorder, depending on the district. The target sample size was 200 (depression and AUD), or 150 (psychosis and epilepsy) patients initiating treatment in each recruiting district. Data collection activities were conducted by PRIME research teams. Participants completed follow-up assessments after 3 months (AUD and depression) or 6 months (psychosis and epilepsy), and after 12 months. Primary outcomes were impaired functioning, using the 12-item World Health Organization Disability Assessment Schedule 2.0 (WHODAS), and symptom severity, assessed using the Patient Health Questionnaire (depression), the Alcohol Use Disorder Identification Test (AUD), and number of seizures (epilepsy). Discussion Cohort recruitment was a function of the clinical detection rate by primary health care staff, and did not meet all planned targets. The cross-country methodology reflected the pragmatic nature of the PRIME cohorts: while the heterogeneity in methods of recruitment was a consequence of differences in health systems and MHCPs, the use of the WHODAS as primary outcome measure will allow for comparison of functioning recovery across sites and disorders.
dc.language.iso en
dc.publisher BioMed Central
dc.source BMC Psychiatry
dc.source.uri https://bmcpsychiatry.biomedcentral.com/
dc.subject.other Cohort; depression
dc.subject.other Alcohol dependence
dc.subject.other Psychosis
dc.subject.other Epilepsy
dc.subject.other Low-income populations
dc.subject.other Primary healthcare
dc.title Impact of district mental health care plans on symptom severity and functioning of patients with priority mental health conditions: the Programme for Improving Mental Health Care (PRIME) cohort protocol
dc.type Journal Article
dc.date.updated 2018-04-09T15:11:04Z
dc.rights.holder The Author(s).
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Centre for Public Mental Health en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Baron, E. C., Rathod, S. D., Hanlon, C., Prince, M., Fedaku, A., Kigozi, F., ... De Silva, M. (2018). Impact of district mental health care plans on symptom severity and functioning of patients with priority mental health conditions: the Programme for Improving Mental Health Care (PRIME) cohort protocol. <i>BMC Psychiatry</i>, http://hdl.handle.net/11427/27927 en_ZA
dc.identifier.chicagocitation Baron, Emily C, Sujit D Rathod, Charlotte Hanlon, Martin Prince, Abebaw Fedaku, Fred Kigozi, Mark Jordans, et al "Impact of district mental health care plans on symptom severity and functioning of patients with priority mental health conditions: the Programme for Improving Mental Health Care (PRIME) cohort protocol." <i>BMC Psychiatry</i> (2018) http://hdl.handle.net/11427/27927 en_ZA
dc.identifier.vancouvercitation Baron EC, Rathod SD, Hanlon C, Prince M, Fedaku A, Kigozi F, et al. Impact of district mental health care plans on symptom severity and functioning of patients with priority mental health conditions: the Programme for Improving Mental Health Care (PRIME) cohort protocol. BMC Psychiatry. 2018; http://hdl.handle.net/11427/27927. en_ZA
dc.identifier.ris TY - Journal Article AU - Baron, Emily C AU - Rathod, Sujit D AU - Hanlon, Charlotte AU - Prince, Martin AU - Fedaku, Abebaw AU - Kigozi, Fred AU - Jordans, Mark AU - Luitel, Nagendra P AU - Medhin, Girmay AU - Murhar, Vaibhav AU - Nakku, Juliet AU - Patel, Vikram AU - Petersen, Inge AU - Selohilwe, One AU - Shidhaye, Rahul AU - Ssebunnya, Joshua AU - Tomlinson, Mark AU - Lund, Crick AU - De Silva, Mary AB - Background The Programme for Improving Mental Health Care (PRIME) sought to implement mental health care plans (MHCP) for four priority mental disorders (depression, alcohol use disorder, psychosis and epilepsy) into routine primary care in five low- and middle-income country districts. The impact of the MHCPs on disability was evaluated through establishment of priority disorder treatment cohorts. This paper describes the methodology of these PRIME cohorts. Methods One cohort for each disorder was recruited across some or all five districts: Sodo (Ethiopia), Sehore (India), Chitwan (Nepal), Dr. Kenneth Kaunda (South Africa) and Kamuli (Uganda), comprising 17 treatment cohorts in total (N = 2182). Participants were adults residing in the districts who were eligible to receive mental health treatment according to primary health care staff, trained by PRIME facilitators as per the district MHCP. Patients who screened positive for depression or AUD and who were not given a diagnosis by their clinicians (N = 709) were also recruited into comparison cohorts in Ethiopia, India, Nepal and South Africa. Caregivers of patients with epilepsy or psychosis were also recruited (N = 953), together with or on behalf of the person with a mental disorder, depending on the district. The target sample size was 200 (depression and AUD), or 150 (psychosis and epilepsy) patients initiating treatment in each recruiting district. Data collection activities were conducted by PRIME research teams. Participants completed follow-up assessments after 3 months (AUD and depression) or 6 months (psychosis and epilepsy), and after 12 months. Primary outcomes were impaired functioning, using the 12-item World Health Organization Disability Assessment Schedule 2.0 (WHODAS), and symptom severity, assessed using the Patient Health Questionnaire (depression), the Alcohol Use Disorder Identification Test (AUD), and number of seizures (epilepsy). Discussion Cohort recruitment was a function of the clinical detection rate by primary health care staff, and did not meet all planned targets. The cross-country methodology reflected the pragmatic nature of the PRIME cohorts: while the heterogeneity in methods of recruitment was a consequence of differences in health systems and MHCPs, the use of the WHODAS as primary outcome measure will allow for comparison of functioning recovery across sites and disorders. DA - 2018-03-06 DB - OpenUCT DO - 10.1186/s12888-018-1642-x DP - University of Cape Town J1 - BMC Psychiatry LK - https://open.uct.ac.za PB - University of Cape Town PY - 2018 T1 - Impact of district mental health care plans on symptom severity and functioning of patients with priority mental health conditions: the Programme for Improving Mental Health Care (PRIME) cohort protocol TI - Impact of district mental health care plans on symptom severity and functioning of patients with priority mental health conditions: the Programme for Improving Mental Health Care (PRIME) cohort protocol UR - http://hdl.handle.net/11427/27927 ER - en_ZA


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