Magnesium sulphate reversal of established bupivacaine electrophysiological cardiotoxicity

 

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dc.contributor.advisor James, Michael F M en_ZA
dc.contributor.author Reed, Anthony Raddon en_ZA
dc.date.accessioned 2018-01-25T13:57:23Z
dc.date.available 2018-01-25T13:57:23Z
dc.date.issued 1998 en_ZA
dc.identifier.citation Reed, A. 1998. Magnesium sulphate reversal of established bupivacaine electrophysiological cardiotoxicity. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/26985
dc.description.abstract The results of this study show that in intact rats magnesium produces a more rapid resolution of bupivacaine induced electrophysiological changes than placebo. The improvements are in rhythm and electrical conduction, although this is often at the expense of potentiating the bradycardic effects of bupivacaine toxicity. Whilst the bradycardia remains a problem it is potentially more amenable to therapy than the changes in rhythm and conduction which magnesium sulphate reversed. The opportunity therefore exists to explore the possibility of combining magnesium with a positive chronotrophic agent such as dobutamine. en_ZA
dc.language.iso eng en_ZA
dc.subject.other Anaesthesia en_ZA
dc.title Magnesium sulphate reversal of established bupivacaine electrophysiological cardiotoxicity en_ZA
dc.type Thesis / Dissertation en_ZA
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Anaesthesia en_ZA
dc.type.qualificationlevel Masters en_ZA
dc.type.qualificationname MMed en_ZA
uct.type.filetype Text
uct.type.filetype Image


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