dc.contributor.author |
Hussey, Hannah
|
|
dc.contributor.author |
Abdullahi, Leila
|
|
dc.contributor.author |
Collins, Jamie
|
|
dc.contributor.author |
Muloiwa, Rudzani
|
|
dc.contributor.author |
Hussey, Gregory
|
|
dc.contributor.author |
Kagina, Benjamin
|
|
dc.date.accessioned |
2017-12-15T07:22:01Z |
|
dc.date.available |
2017-12-15T07:22:01Z |
|
dc.date.issued |
2017-11-14 |
|
dc.identifier.citation |
Hussey, H., Abdullahi, L., Collins, J., Muloiwa, R., Hussey, G., & Kagina, B. (2017). Varicella zoster virus-associated morbidity and mortality in Africa–a systematic review. BMC infectious diseases, 17(1), 717. |
|
dc.identifier.uri |
http://dx.doi.org/10.1186/s12879-017-2815-9
|
|
dc.identifier.uri |
http://hdl.handle.net/11427/26713
|
|
dc.description.abstract |
Background: Varicella zoster virus (VZV) causes varicella and herpes zoster. These vaccine preventable diseases are common globally. Most available data on VZV epidemiology are from industrialised temperate countries and cannot be used to guide decisions on the immunization policy against VZV in Africa. This systematic review aims to review the published data on VZV morbidity and mortality in Africa. Methods: All published studies conducted in Africa from 1974 to 2015 were eligible. Eligible studies must have reported any VZV epidemiological measure (incidence, prevalence, hospitalization rate and mortality rate). For inclusion in the review, studies must have used a defined VZV case definition, be it clinical or laboratory-based. Results: Twenty articles from 13 African countries were included in the review. Most included studies were crosssectional, conducted on hospitalized patients, and half of the studies used varying serological methods for diagnosis. VZV seroprevalence was very high among adults. Limited data on VZV seroprevalence in children showed very low seropositivity to anti-VZV antibodies. Co-morbidity with VZV was common. Conclusion: There is lack of quality data that could be used to develop VZV control programmes, including vaccination, in Africa. Trial registration: PROSPERO 2015: CRD42015026144. |
|
dc.language.iso |
en |
|
dc.publisher |
BioMed Central |
|
dc.source |
BMC Infectious Diseases |
|
dc.source.uri |
https://bmcinfectdis.biomedcentral.com/
|
|
dc.subject.other |
Varicella |
|
dc.subject.other |
Zoster |
|
dc.subject.other |
Shingles |
|
dc.subject.other |
Chickenpox |
|
dc.subject.other |
Africa |
|
dc.subject.other |
Epidemiology |
|
dc.title |
Varicella zoster virus-associated morbidity and mortality in Africa – a systematic review |
|
dc.type |
Journal Article |
|
dc.date.updated |
2017-11-19T04:26:29Z |
|
dc.rights.holder |
The Author(s). |
|
dc.publisher.institution |
University of Cape Town |
|
dc.publisher.faculty |
Faculty of Health Sciences |
en_ZA |
dc.publisher.department |
Division of Medical Microbiology |
en_ZA |
uct.type.filetype |
Text |
|
uct.type.filetype |
Image |
|
dc.identifier.apacitation |
Hussey, H., Abdullahi, L., Collins, J., Muloiwa, R., Hussey, G., & Kagina, B. (2017). Varicella zoster virus-associated morbidity and mortality in Africa – a systematic review. <i>BMC Infectious Diseases</i>, http://hdl.handle.net/11427/26713 |
en_ZA |
dc.identifier.chicagocitation |
Hussey, Hannah, Leila Abdullahi, Jamie Collins, Rudzani Muloiwa, Gregory Hussey, and Benjamin Kagina "Varicella zoster virus-associated morbidity and mortality in Africa – a systematic review." <i>BMC Infectious Diseases</i> (2017) http://hdl.handle.net/11427/26713 |
en_ZA |
dc.identifier.vancouvercitation |
Hussey H, Abdullahi L, Collins J, Muloiwa R, Hussey G, Kagina B. Varicella zoster virus-associated morbidity and mortality in Africa – a systematic review. BMC Infectious Diseases. 2017; http://hdl.handle.net/11427/26713. |
en_ZA |
dc.identifier.ris |
TY - Journal Article
AU - Hussey, Hannah
AU - Abdullahi, Leila
AU - Collins, Jamie
AU - Muloiwa, Rudzani
AU - Hussey, Gregory
AU - Kagina, Benjamin
AB - Background: Varicella zoster virus (VZV) causes varicella and herpes zoster. These vaccine preventable diseases are common globally. Most available data on VZV epidemiology are from industrialised temperate countries and cannot be used to guide decisions on the immunization policy against VZV in Africa. This systematic review aims to review the published data on VZV morbidity and mortality in Africa. Methods: All published studies conducted in Africa from 1974 to 2015 were eligible. Eligible studies must have reported any VZV epidemiological measure (incidence, prevalence, hospitalization rate and mortality rate). For inclusion in the review, studies must have used a defined VZV case definition, be it clinical or laboratory-based. Results: Twenty articles from 13 African countries were included in the review. Most included studies were crosssectional, conducted on hospitalized patients, and half of the studies used varying serological methods for diagnosis. VZV seroprevalence was very high among adults. Limited data on VZV seroprevalence in children showed very low seropositivity to anti-VZV antibodies. Co-morbidity with VZV was common. Conclusion: There is lack of quality data that could be used to develop VZV control programmes, including vaccination, in Africa. Trial registration: PROSPERO 2015: CRD42015026144.
DA - 2017-11-14
DB - OpenUCT
DO - 10.1186/s12879-017-2815-9
DP - University of Cape Town
J1 - BMC Infectious Diseases
LK - https://open.uct.ac.za
PB - University of Cape Town
PY - 2017
T1 - Varicella zoster virus-associated morbidity and mortality in Africa – a systematic review
TI - Varicella zoster virus-associated morbidity and mortality in Africa – a systematic review
UR - http://hdl.handle.net/11427/26713
ER -
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en_ZA |