Leaving the party - withdrawal of South African essential medicines

 

Show simple item record

dc.contributor.author Wilmshurst, Jo M
dc.contributor.author Blockman, Marc
dc.contributor.author Argent, Andrew
dc.contributor.author Gordon-Graham, Eugenie
dc.contributor.author Thomas, Jenny
dc.contributor.author Whitelaw, Andrew
dc.contributor.author McCulloch, Mignon
dc.contributor.author Ramiah, Malitha
dc.contributor.author Dyeshana, H
dc.contributor.author Ireland, Joe
dc.date.accessioned 2017-10-25T07:11:11Z
dc.date.available 2017-10-25T07:11:11Z
dc.date.issued 2005
dc.identifier.citation Wilmshurst, J. M., Blockman, M., Argent, A., Gordon-Graham, E., Thomas, J., Whitelaw, A., ... & Ireland, J. (2006). Leaving the party-withdrawal of South African essential medicines: editorial. South African Medical Journal, 96(5), p-419.
dc.identifier.uri http://hdl.handle.net/11427/25753
dc.description.abstract In August 2004 pharmacies and drug depots were advised that the sole supplier of parenteral phenobarbitone in South Africa, essential for the management of status epilepticus in children, was stopping production at the end of the same year. Alternative protocols for the management of status epilepticus resulted in more children requiring intensive care intervention (N = 9) at the Red Cross Children’s Hospital, over a 2-month period, than had occurred in any 12-month period since 2000 (2000 N = 3, 2001 N = 1, 2002 N = 1, 2003 N = 2, 2004 N = 7). Other agents that have suffered or are at risk of the same fate are sodium nitroprusside, labetalol and esmolol. Sodium nitroprusside is used extensively in the peri-operative period in cardiac patients requiring after-load reduction. There are no other nitrates with equivalent efficacy. Supply was stopped in 2005 and only reinstated after the pharmaceutical company was contacted directly. Supply of labetalol and esmolol was stopped without warning. Without access to these products it is necessary to resort to agents that are not appropriate for paediatric use. Acetylcysteine (Parvolex), used in the management of acetaminophen overdose, also became unavailable and the supply was re-established only after direct communication with the pharmaceutical company.
dc.source South African Medical Journal
dc.title Leaving the party - withdrawal of South African essential medicines
dc.type Journal Article
dc.date.updated 2016-01-13T07:31:55Z
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Medicine en_ZA
uct.type.filetype
uct.type.filetype Text


Files in this item

This item appears in the following Collection(s)

Show simple item record