An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008

 

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dc.contributor.advisor Denny, Lynette en_ZA
dc.contributor.advisor van Wijk, Leon en_ZA
dc.contributor.author Hendricks, Aneeqah en_ZA
dc.date.accessioned 2017-09-22T12:01:55Z
dc.date.available 2017-09-22T12:01:55Z
dc.date.issued 2017 en_ZA
dc.identifier.citation Hendricks, A. 2017. An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/25292
dc.description.abstract Background: Borderline ovarian tumours (BOT) are an intermediate form of neoplasia, between benign and malignant and have been classified as epithelial tumours of low malignant potential. These particular tumours affect a younger age group than their invasive counterparts with an overall survival of 90 - 100%. The present study aims to document the experience of a single centre on the management of women with borderline ovarian tumours (BOT). Methods: Two hundred and thirteen patients diagnosed and treated with BOT between 1984 and 2008 were identified through the Gynaecology Oncology database that has been in existence since 1984. Details of management, outcome and survival were retrieved and data were analysed descriptively and for survival. Results: The median age at diagnosis was 45 years old, with 34 % of patients > 40 years old. The incidence of serous BOT (SBOT) was 47.9% (102/213) and 49.3 % (105/213) were mucinous BOT (MBOT). Most of the patients were diagnosed in Stage I 83.6% (178/213), 6.1%( 13/213) were in stage II and 10.0% (22/213) were stage III. There were no patients in stage IV. At the end of the study period 73% (156/213) of the women were alive with no evidence of disease. Univariate analysis, indicated that the histological subtype of tumour, the type of surgery, the presence of residual disease, advanced stage disease, the presence of ascites were all statistically significant in affecting survival. Multivariate analysis, however, revealed that only the presence of residual disease was statistically significant as a prognostic predictor of poor outcome. en_ZA
dc.language.iso eng en_ZA
dc.subject.other Gynaecology en_ZA
dc.title An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008 en_ZA
dc.type Master Thesis
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Obstetrics and Gynaecology en_ZA
dc.type.qualificationlevel Masters
dc.type.qualificationname MMed en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Hendricks, A. (2017). <i>An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Obstetrics and Gynaecology. Retrieved from http://hdl.handle.net/11427/25292 en_ZA
dc.identifier.chicagocitation Hendricks, Aneeqah. <i>"An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Obstetrics and Gynaecology, 2017. http://hdl.handle.net/11427/25292 en_ZA
dc.identifier.vancouvercitation Hendricks A. An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Obstetrics and Gynaecology, 2017 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/25292 en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Hendricks, Aneeqah AB - Background: Borderline ovarian tumours (BOT) are an intermediate form of neoplasia, between benign and malignant and have been classified as epithelial tumours of low malignant potential. These particular tumours affect a younger age group than their invasive counterparts with an overall survival of 90 - 100%. The present study aims to document the experience of a single centre on the management of women with borderline ovarian tumours (BOT). Methods: Two hundred and thirteen patients diagnosed and treated with BOT between 1984 and 2008 were identified through the Gynaecology Oncology database that has been in existence since 1984. Details of management, outcome and survival were retrieved and data were analysed descriptively and for survival. Results: The median age at diagnosis was 45 years old, with 34 % of patients > 40 years old. The incidence of serous BOT (SBOT) was 47.9% (102/213) and 49.3 % (105/213) were mucinous BOT (MBOT). Most of the patients were diagnosed in Stage I 83.6% (178/213), 6.1%( 13/213) were in stage II and 10.0% (22/213) were stage III. There were no patients in stage IV. At the end of the study period 73% (156/213) of the women were alive with no evidence of disease. Univariate analysis, indicated that the histological subtype of tumour, the type of surgery, the presence of residual disease, advanced stage disease, the presence of ascites were all statistically significant in affecting survival. Multivariate analysis, however, revealed that only the presence of residual disease was statistically significant as a prognostic predictor of poor outcome. DA - 2017 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2017 T1 - An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008 TI - An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008 UR - http://hdl.handle.net/11427/25292 ER - en_ZA


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