Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa

 

Show simple item record

dc.contributor.author Adeola, Henry A
dc.contributor.author Soyele, Olujide O
dc.contributor.author Adefuye, Anthonio O
dc.contributor.author Jimoh, Sikiru A
dc.contributor.author Butali, Azeez
dc.date.accessioned 2017-06-13T06:36:30Z
dc.date.available 2017-06-13T06:36:30Z
dc.date.issued 2017-06-05
dc.identifier.citation Adeola, H. A., Soyele, O. O., Adefuye, A. O., Jimoh, S. A., & Butali, A. (2017). Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa. Cancer Cell International, 17(1), 61.
dc.identifier.uri http://dx.doi.org/10.1186/s12935-017-0432-8
dc.identifier.uri http://hdl.handle.net/11427/24565
dc.description.abstract Background: The completion of the human genome project and the accomplished milestones in the human proteome project; as well as the progress made so far in computational bioinformatics and “big data” processing have contributed immensely to individualized/personalized medicine in the developed world. Main body: At the dawn of precision medicine, various omics-based therapies and bioengineering can now be applied accurately for the diagnosis, prognosis, treatment, and risk stratifcation of cancer in a manner that was hitherto not thought possible. The widespread introduction of genomics and other omics-based approaches into the postgraduate training curriculum of diverse medical and dental specialties, including pathology has improved the profciency of practitioners in the use of novel molecular signatures in patient management. In addition, intricate details about disease disparity among diferent human populations are beginning to emerge. This would facilitate the use of tailor-made novel theranostic methods based on emerging molecular evidences. Conclusion: In this review, we examined the challenges and prospects of using currently available omics-based technologies vis-à-vis oral pathology as well as prompt cancer diagnosis and treatment in a resource limited setting.
dc.language.iso en
dc.publisher BioMed Central
dc.source Cancer Cell International
dc.source.uri https://cancerci.biomedcentral.com/
dc.subject.other Omics-based
dc.subject.other Molecular
dc.subject.other Developing world
dc.subject.other Oral pathology
dc.subject.other Challenges
dc.title Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa
dc.type Journal Article
dc.date.updated 2017-06-11T03:14:53Z
dc.rights.holder The Author(s)
uct.type.publication Research en_ZA
uct.type.resource Article en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Division of Dermatology en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Adeola, H. A., Soyele, O. O., Adefuye, A. O., Jimoh, S. A., & Butali, A. (2017). Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa. <i>Cancer Cell International</i>, http://hdl.handle.net/11427/24565 en_ZA
dc.identifier.chicagocitation Adeola, Henry A, Olujide O Soyele, Anthonio O Adefuye, Sikiru A Jimoh, and Azeez Butali "Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa." <i>Cancer Cell International</i> (2017) http://hdl.handle.net/11427/24565 en_ZA
dc.identifier.vancouvercitation Adeola HA, Soyele OO, Adefuye AO, Jimoh SA, Butali A. Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa. Cancer Cell International. 2017; http://hdl.handle.net/11427/24565. en_ZA
dc.identifier.ris TY - Journal Article AU - Adeola, Henry A AU - Soyele, Olujide O AU - Adefuye, Anthonio O AU - Jimoh, Sikiru A AU - Butali, Azeez AB - Background: The completion of the human genome project and the accomplished milestones in the human proteome project; as well as the progress made so far in computational bioinformatics and “big data” processing have contributed immensely to individualized/personalized medicine in the developed world. Main body: At the dawn of precision medicine, various omics-based therapies and bioengineering can now be applied accurately for the diagnosis, prognosis, treatment, and risk stratifcation of cancer in a manner that was hitherto not thought possible. The widespread introduction of genomics and other omics-based approaches into the postgraduate training curriculum of diverse medical and dental specialties, including pathology has improved the profciency of practitioners in the use of novel molecular signatures in patient management. In addition, intricate details about disease disparity among diferent human populations are beginning to emerge. This would facilitate the use of tailor-made novel theranostic methods based on emerging molecular evidences. Conclusion: In this review, we examined the challenges and prospects of using currently available omics-based technologies vis-à-vis oral pathology as well as prompt cancer diagnosis and treatment in a resource limited setting. DA - 2017-06-05 DB - OpenUCT DO - 10.1186/s12935-017-0432-8 DP - University of Cape Town J1 - Cancer Cell International LK - https://open.uct.ac.za PB - University of Cape Town PY - 2017 T1 - Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa TI - Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa UR - http://hdl.handle.net/11427/24565 ER - en_ZA


Files in this item

This item appears in the following Collection(s)

Show simple item record