Cutaneous cryptococcosis erroneously diagnosed as histoplasma capsulatum infection

 

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dc.contributor.author Chipungu, Geoffrey A
dc.contributor.author Christians, Sean J
dc.contributor.author Oliver, Stephen P
dc.date.accessioned 2017-05-17T09:35:59Z
dc.date.available 2017-05-17T09:35:59Z
dc.date.issued 2008
dc.identifier.citation Chipungu, G. A., Christians, S. J., & Oliver, S. P. (2008). Cutaneous cryptococcosis erroneously diagnosed as Histoplasma capsulatum infection: clinical images: SAMJ forum. South African Medical Journal, 98(2), 85-86.
dc.identifier.uri http://hdl.handle.net/11427/24342
dc.description.abstract A 31-year-old patient with stage 4 HIV/AIDS presented with recurrent painful skin ulcers for more than 8 months. These would start as subcutaneous skin nodules, later becoming fluctuant and suppurating and then healing spontaneously (Fig. 1). The patient had lesions on the left wrist, left posterior thigh, right axilla, right posterior calf and right upper eyelid. He had also been diagnosed with extrapulmonary tuberculosis and had been on highly active antiretroviral therapy (HAART) for 8 months and antituberculosis medication (continuation phase). After initial poor adherence to both groups of drugs, compliance had improved. The CD4 count at baseline was 16 cells/µl and the latest result was 80 cells/µl. Histological analysis of a biopsy specimen taken from the right upper eyelid lesion showed granulation tissue with some acute inflammation. Fungal spores were seen in the exudates and stains revealed ‘capsule-deficient’ fungi that were first thought to be Histoplasma, and were reported as such.
dc.language.iso eng
dc.source South African Medical Journal
dc.source.uri http://www.samj.org.za/index.php/samj
dc.title Cutaneous cryptococcosis erroneously diagnosed as histoplasma capsulatum infection
dc.type Journal Article en_ZA
dc.date.updated 2016-01-08T07:29:17Z
uct.type.publication Research en_ZA
uct.type.resource Article en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Medicine en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Chipungu, G. A., Christians, S. J., & Oliver, S. P. (2008). Cutaneous cryptococcosis erroneously diagnosed as histoplasma capsulatum infection. <i>South African Medical Journal</i>, http://hdl.handle.net/11427/24342 en_ZA
dc.identifier.chicagocitation Chipungu, Geoffrey A, Sean J Christians, and Stephen P Oliver "Cutaneous cryptococcosis erroneously diagnosed as histoplasma capsulatum infection." <i>South African Medical Journal</i> (2008) http://hdl.handle.net/11427/24342 en_ZA
dc.identifier.vancouvercitation Chipungu GA, Christians SJ, Oliver SP. Cutaneous cryptococcosis erroneously diagnosed as histoplasma capsulatum infection. South African Medical Journal. 2008; http://hdl.handle.net/11427/24342. en_ZA
dc.identifier.ris TY - Journal Article AU - Chipungu, Geoffrey A AU - Christians, Sean J AU - Oliver, Stephen P AB - A 31-year-old patient with stage 4 HIV/AIDS presented with recurrent painful skin ulcers for more than 8 months. These would start as subcutaneous skin nodules, later becoming fluctuant and suppurating and then healing spontaneously (Fig. 1). The patient had lesions on the left wrist, left posterior thigh, right axilla, right posterior calf and right upper eyelid. He had also been diagnosed with extrapulmonary tuberculosis and had been on highly active antiretroviral therapy (HAART) for 8 months and antituberculosis medication (continuation phase). After initial poor adherence to both groups of drugs, compliance had improved. The CD4 count at baseline was 16 cells/µl and the latest result was 80 cells/µl. Histological analysis of a biopsy specimen taken from the right upper eyelid lesion showed granulation tissue with some acute inflammation. Fungal spores were seen in the exudates and stains revealed ‘capsule-deficient’ fungi that were first thought to be Histoplasma, and were reported as such. DA - 2008 DB - OpenUCT DP - University of Cape Town J1 - South African Medical Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2008 T1 - Cutaneous cryptococcosis erroneously diagnosed as histoplasma capsulatum infection TI - Cutaneous cryptococcosis erroneously diagnosed as histoplasma capsulatum infection UR - http://hdl.handle.net/11427/24342 ER - en_ZA


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