dc.contributor.advisor |
Franz , Thomas |
en_ZA |
dc.contributor.advisor |
Davies, Neil |
en_ZA |
dc.contributor.advisor |
Dubuis, Laura |
en_ZA |
dc.contributor.author |
Masithulela, Fulufhelo James
|
en_ZA |
dc.date.accessioned |
2016-07-21T11:01:14Z |
|
dc.date.available |
2016-07-21T11:01:14Z |
|
dc.date.issued |
2016 |
en_ZA |
dc.identifier.citation |
Masithulela, F. 2016. Computational biomechanics in the remodelling rat heart post myocardial infarction. University of Cape Town. |
en_ZA |
dc.identifier.uri |
http://hdl.handle.net/11427/20555
|
|
dc.description.abstract |
Cardiovascular diseases account for one third of all deaths worldwide, more than 33% of which are related to ischemic heart disease, including myocardial infarction (MI). This thesis seeks to provide insight and understanding of mechanisms during different stages of MI by utilizing finite element (FE) modelling. Three-dimensional biventricular rat heart geometries were developed from cardiac magnetic resonance images of a healthy heart and a heart with left ventricular (LV) infarction two weeks and four weeks after infarct induction. From these geometries, FE models were established. To represent the myocardium, a structure-based constitutive model and a rule-based myofibre distribution were developed to simulate both passive mechanics and active contraction. |
en_ZA |
dc.language.iso |
eng |
en_ZA |
dc.subject.other |
Cardiovascular Biomechanics |
en_ZA |
dc.title |
Computational biomechanics in the remodelling rat heart post myocardial infarction |
en_ZA |
dc.type |
Doctoral Thesis |
|
uct.type.publication |
Research |
en_ZA |
uct.type.resource |
Thesis
|
en_ZA |
dc.publisher.institution |
University of Cape Town |
|
dc.publisher.faculty |
Faculty of Health Sciences |
en_ZA |
dc.publisher.department |
Division of Cardiology |
en_ZA |
dc.type.qualificationlevel |
Doctoral |
|
dc.type.qualificationname |
PhD |
en_ZA |
uct.type.filetype |
Text |
|
uct.type.filetype |
Image |
|
dc.identifier.apacitation |
Masithulela, F. J. (2016). <i>Computational biomechanics in the remodelling rat heart post myocardial infarction</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Cardiology. Retrieved from http://hdl.handle.net/11427/20555 |
en_ZA |
dc.identifier.chicagocitation |
Masithulela, Fulufhelo James. <i>"Computational biomechanics in the remodelling rat heart post myocardial infarction."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Cardiology, 2016. http://hdl.handle.net/11427/20555 |
en_ZA |
dc.identifier.vancouvercitation |
Masithulela FJ. Computational biomechanics in the remodelling rat heart post myocardial infarction. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Cardiology, 2016 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/20555 |
en_ZA |
dc.identifier.ris |
TY - Thesis / Dissertation
AU - Masithulela, Fulufhelo James
AB - Cardiovascular diseases account for one third of all deaths worldwide, more than 33% of which are related to ischemic heart disease, including myocardial infarction (MI). This thesis seeks to provide insight and understanding of mechanisms during different stages of MI by utilizing finite element (FE) modelling. Three-dimensional biventricular rat heart geometries were developed from cardiac magnetic resonance images of a healthy heart and a heart with left ventricular (LV) infarction two weeks and four weeks after infarct induction. From these geometries, FE models were established. To represent the myocardium, a structure-based constitutive model and a rule-based myofibre distribution were developed to simulate both passive mechanics and active contraction.
DA - 2016
DB - OpenUCT
DP - University of Cape Town
LK - https://open.uct.ac.za
PB - University of Cape Town
PY - 2016
T1 - Computational biomechanics in the remodelling rat heart post myocardial infarction
TI - Computational biomechanics in the remodelling rat heart post myocardial infarction
UR - http://hdl.handle.net/11427/20555
ER -
|
en_ZA |