Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve

 

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dc.contributor.author Hendricks, Marc
dc.contributor.author Van Eyssen, Ann Louise
dc.date.accessioned 2016-05-19T12:43:01Z
dc.date.available 2016-05-19T12:43:01Z
dc.date.issued 2012
dc.identifier http://dx.doi.org/10.7196/SAJCH.458
dc.identifier.citation van Eyssen, A. L., & Hendricks, M. (2012). Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve. South African Journal of Child Health, 6(3), 85-87. en_ZA
dc.identifier.issn 1999-7671 en_ZA
dc.identifier.uri http://hdl.handle.net/11427/19721
dc.identifier.uri http://sajch.org.za/index.php/SAJCH/article/view/458
dc.description.abstract We report a case of a 2-year-old boy presenting with persistent fever and splenomegaly who fulfilled the diagnostic criteria for haemophagocytic lymphohistiocytosis (HLH) according to the Histiocyte Society (2004). The persistence of a cardiac murmur despite multiple transfusions, and therapy which rendered him afebrile, led us to do an echocardiogram as part of surveillance for sepsis. This revealed tricuspid vegetation and a small ventricular septal defect. Blood culture and postoperative histology of the anterior leaflet of the tricuspid valve confirmed Streptococcus pneumoniae infection. The patient was successfully treated with intravenous antibiotic therapy for 6 weeks and dexamethasone for 8 weeks and remains well and in remission (from HLH) a year later with residual tricuspid regurgitation awaiting tricuspid valve replacement. en_ZA
dc.language eng en_ZA
dc.publisher Health and Medical Publishing Group en_ZA
dc.rights Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) *
dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/ en_ZA
dc.source South African Journal of Child Health en_ZA
dc.source.uri http://www.sajch.org.za/index.php/SAJCH
dc.subject.other haemophagocytic lymphohistiocytosis
dc.subject.other pneumococcal endocarditis
dc.title Haemophagocytic lymphohistiocytosis following culture-proven pneumococcal infective endocarditis of the tricuspid valve en_ZA
dc.type Journal Article en_ZA
dc.date.updated 2016-05-19T12:36:09Z
uct.type.publication Research en_ZA
uct.type.resource Article en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Paediatrics and Child Health en_ZA
uct.type.filetype Text
uct.type.filetype Image


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Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Except where otherwise noted, this item's license is described as Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)