Exercise tolerance and skeletal muscle structure and function in patients with chronic obstructive pulminary disease

Master Thesis

1998

Permanent link to this Item
http://hdl.handle.net/11427/17935
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thesis_hsf_1998_coleman_kirsty_lee.pdf (3.7 MB)
Authors
Coleman, Kirsty Lee
Supervisors
Derman, Wayne
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University of Cape Town

Department
MRC/UCT RU for Exercise and Sport Medicine
Faculty
Faculty of Health Sciences
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Abstract
Exercise intolerance is well documented in patients with chronic obstructive pulmonary disease (COPD). Historically, this exercise intolerance has been attributed to the central factors of lung damage and subsequent heart failure. However, recent evidence suggests that (i) patients with cardiac and renal failure suffer from skeletal muscle (SM) abnormalities that impair exercise tolerance and (ii) patients with chronic obstructive pulmonary disease (COPD) may have metabolic and functional abnormalities of SM. However, no studies have conducted a detailed investigation of SM structure and function and their relation to exercise tolerance in patients with COPD.
Description

Bibliography: pages 143-154.

Keywords
Exercise Science

Reference:

Coleman, K. 1998. Exercise tolerance and skeletal muscle structure and function in patients with chronic obstructive pulminary disease. University of Cape Town.

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