Studies directed towards the synthesis of metal-containing ketones

 

Show simple item record

dc.contributor.advisor Cragg, G M L en_ZA
dc.contributor.advisor Haines, Raymond J en_ZA
dc.contributor.author Davidowitz, Bette en_ZA
dc.date.accessioned 2016-03-17T07:18:53Z
dc.date.available 2016-03-17T07:18:53Z
dc.date.issued 1977 en_ZA
dc.identifier.citation Davidowitz, B. 1977. Studies directed towards the synthesis of metal-containing ketones. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/17904
dc.description.abstract The photochemistry of organometallic compounds is receiving increasing attention in the current literature, but as yet, little work has been reported on the photochemistry of metal-containing ketones. The objective of the work reported in this thesis was the synthesis of ligands for the formation of suitable metal-containing ketones. The initial studies were directed at the preparation of β- and ϒ-hydroxyketones by a variety of methods, but the major effort was later concentrated on the synthesis of phosphorus derivatives of o-hydroxyphenyl alkyl ketones . The reaction of o-hydroxyphenyl alkyl ketones with phosphorus trichloride afforded 2-chloro- 1,3,2-dioxaphosphorinans which were readily converted to the corresponding 2-alkoxy derivatives by reaction with various alcohols. Extension of the study to acteylacetone indicated that an analogous reaction occurs to give highly labile products. This part of the work has been accepted for publication in Chemical Communications. The reaction of o-hydroxyphenyl alkyl ketones with other phosphorus halides, such as dichlorophenyl phosphine and chlorodiphenylphosphine, has also been investigated. Reaction of the former reagent with o-hydroxyacetophenone gave a crystalline phosphorus-containing derivative; spectroscopic evidence indicates that this compound possesses an unusual structure and it is currently being studied by X-ray crystallography. en_ZA
dc.language.iso eng en_ZA
dc.subject.other Chemistry en_ZA
dc.subject.other Organic Chemistry en_ZA
dc.title Studies directed towards the synthesis of metal-containing ketones en_ZA
dc.type Master Thesis
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Science en_ZA
dc.publisher.department Department of Chemistry en_ZA
dc.type.qualificationlevel Masters
dc.type.qualificationname MSc en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Davidowitz, B. (1977). <i>Studies directed towards the synthesis of metal-containing ketones</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Chemistry. Retrieved from http://hdl.handle.net/11427/17904 en_ZA
dc.identifier.chicagocitation Davidowitz, Bette. <i>"Studies directed towards the synthesis of metal-containing ketones."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Chemistry, 1977. http://hdl.handle.net/11427/17904 en_ZA
dc.identifier.vancouvercitation Davidowitz B. Studies directed towards the synthesis of metal-containing ketones. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Chemistry, 1977 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/17904 en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Davidowitz, Bette AB - The photochemistry of organometallic compounds is receiving increasing attention in the current literature, but as yet, little work has been reported on the photochemistry of metal-containing ketones. The objective of the work reported in this thesis was the synthesis of ligands for the formation of suitable metal-containing ketones. The initial studies were directed at the preparation of β- and ϒ-hydroxyketones by a variety of methods, but the major effort was later concentrated on the synthesis of phosphorus derivatives of o-hydroxyphenyl alkyl ketones . The reaction of o-hydroxyphenyl alkyl ketones with phosphorus trichloride afforded 2-chloro- 1,3,2-dioxaphosphorinans which were readily converted to the corresponding 2-alkoxy derivatives by reaction with various alcohols. Extension of the study to acteylacetone indicated that an analogous reaction occurs to give highly labile products. This part of the work has been accepted for publication in Chemical Communications. The reaction of o-hydroxyphenyl alkyl ketones with other phosphorus halides, such as dichlorophenyl phosphine and chlorodiphenylphosphine, has also been investigated. Reaction of the former reagent with o-hydroxyacetophenone gave a crystalline phosphorus-containing derivative; spectroscopic evidence indicates that this compound possesses an unusual structure and it is currently being studied by X-ray crystallography. DA - 1977 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1977 T1 - Studies directed towards the synthesis of metal-containing ketones TI - Studies directed towards the synthesis of metal-containing ketones UR - http://hdl.handle.net/11427/17904 ER - en_ZA


Files in this item

This item appears in the following Collection(s)

Show simple item record