High prevalence of self-reported undiagnosed HIV despite high coverage of HIV testing: a cross-sectional population based sero-survey in South Africa

 

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dc.contributor.author Kranzer, Katharina en_ZA
dc.contributor.author van Schaik, Nienke en_ZA
dc.contributor.author Karmue, Unice en_ZA
dc.contributor.author Middelkoop, Keren en_ZA
dc.contributor.author Sebastian, Elaine en_ZA
dc.contributor.author Lawn, Stephen D en_ZA
dc.contributor.author Wood, Robin en_ZA
dc.contributor.author Bekker, Linda-Gail en_ZA
dc.date.accessioned 2016-01-11T06:50:56Z
dc.date.available 2016-01-11T06:50:56Z
dc.date.issued 2011 en_ZA
dc.identifier.citation Kranzer, K., van Schaik, N., Karmue, U., Middelkoop, K., & Sebastian, E. (2011).High prevalence of self-reported undiagnosed HIV despite high coverage of HIV testing: a cross-sectional population based sero-survey in South Africa.. PLoS ONE, 6(9), e25244. doi:10.1371/journal.pone.0025244 en_ZA
dc.identifier.uri http://hdl.handle.net/11427/16239
dc.identifier.uri http://dx.doi.org/10.1371/journal.pone.0025244
dc.description.abstract Objectives: To measure HIV prevalence and uptake of HIV counseling and testing (HCT) in a peri-urban South African community. To assess predictors for previous HIV testing and the association between the yield of previously undiagnosed HIV and time of last negative HIV test. METHODS: A random sample of 10% of the adult population (≥15 years) were invited to attend a mobile HCT service. Study procedures included a questionnaire, HIV testing and CD4 counts. Predictors for previous testing were determined using a binominal model. RESULTS: 1,144 (88.0%) of 1,300 randomly selected individuals participated in the study. 71.0% (68.3-73.6) had previously had an HIV test and 37.5% (34.6-40.5) had tested in the past 12 months. Men, migrants and older (>35 years) and younger (<20 years) individuals were less likely to have had a previous HIV test. Overall HIV prevalence was 22.7 (20.3-25.3) with peak prevalence of 41.8% (35.8-47.8) in women aged 25.1-35 years and 37.5% (26.7-48.3) in men aged 25.1-45 years. Prevalence of previously undiagnosed HIV was 10.3% (8.5-12.1) overall and 4.5% (2.3-6.6), 8.0% (CI 3.9-12.0) and 20.0% (13.2-26.8) in individuals who had their most recent HIV test within 1, 1-2 and more than 2 years prior to the survey. CONCLUSION: The high burden of undiagnosed HIV in individuals who had recently tested underscores the importance of frequent repeat testing at least annually. The high prevalence of previously undiagnosed HIV in individuals reporting a negative test in the 12 months preceding the survey indicates a very high incidence. Innovative prevention strategies are needed. en_ZA
dc.language.iso eng en_ZA
dc.publisher Public Library of Science en_ZA
dc.rights This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. en_ZA
dc.rights.uri http://creativecommons.org/licenses/by/4.0 en_ZA
dc.source PLoS One en_ZA
dc.source.uri http://journals.plos.org/plosone en_ZA
dc.subject.other HIV en_ZA
dc.subject.other HIV diagnosis and management en_ZA
dc.subject.other HIV infections en_ZA
dc.subject.other HIV prevention en_ZA
dc.subject.other South Africa en_ZA
dc.subject.other HIV epidemiology en_ZA
dc.subject.other Africans en_ZA
dc.subject.other Antiretroviral therapy en_ZA
dc.title High prevalence of self-reported undiagnosed HIV despite high coverage of HIV testing: a cross-sectional population based sero-survey in South Africa en_ZA
dc.type Journal Article en_ZA
dc.rights.holder © 2011 Kranzer et al en_ZA
uct.type.publication Research en_ZA
uct.type.resource Article en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Desmond Tutu HIV Centre en_ZA
uct.type.filetype Text
uct.type.filetype Image


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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Except where otherwise noted, this item's license is described as This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.