Receptor simulation and the shape of the concentration-response curve and its congeners

Journal Article

2003

Permanent link to this Item
Authors
Journal Title

South African Journal of Science

Journal ISSN
Volume Title
Publisher

Academy of Science of South Africa (ASSAf)

Publisher

University of Cape Town

Series
Abstract
We have investigated the utility of curves used to represent concentration (or dose) plotted against response (or effect). We applied crude survival data from our laboratory to demonstrate that a known hyperbolic curve compares favourably with the conventionally used sigmoidal regression in robustness, while avoiding problems associated with the use of transforms.
Description

Reference:

Collections