dc.contributor.author |
Yone, Eric Walter
|
en_ZA |
dc.contributor.author |
Balkissou, Adamou
|
en_ZA |
dc.contributor.author |
Kengne, Andre
|
en_ZA |
dc.contributor.author |
Kuaban, Christopher
|
en_ZA |
dc.date.accessioned |
2015-12-07T08:52:15Z |
|
dc.date.available |
2015-12-07T08:52:15Z |
|
dc.date.issued |
2012 |
en_ZA |
dc.identifier.citation |
Yone, E. W. P., Balkissou, A. D., Kengne, A. P., & Kuaban, C. (2012). Influence of HIV infection on the clinical presentation and outcome of adults with acute community-acquired pneumonia in Yaounde, Cameroon: a retrospective hospital-based study. BMC pulmonary medicine, 12(1), 46. |
en_ZA |
dc.identifier.uri |
http://hdl.handle.net/11427/15657
|
|
dc.identifier.uri |
http://dx.doi.org/10.1186/1471-2466-12-46
|
|
dc.description.abstract |
BACKGROUND: The impact of HIV infection on the evolution of acute community-acquired pneumonia (CAP) is still controversial. The aim of this study was to investigate possible differences in the clinical presentation and in-hospital outcomes of patients with CAP with and without HIV infection in a specialised service in Yaounde. METHODS: Medical files of 106 patients (51 men) aged 15years and above, admitted to the Pneumology service of the Yaounde Jamot Hospital between January 2008 and May 2012, were retrospectively studied. RESULTS: Sixty-two (58.5%) patients were HIV infected. The median age of all patients was 40years (interquartile range: 31.75-53) and there was no difference in the clinical and radiological profile of patients with and without HIV infection. The median leukocyte count (interquartile range) was 14,600/mm3 (10,900-20,600) and 10,450/mm3 (6,400-16,850) respectively in HIV negative and HIV positive patients (p=0.002). Median haemoglobin level (interquartile range) was 10.8g/dl (8.9-12) in HIV negative and 9.7g/dl (8-11.6) in HIV positive patients (p=0.025). In-hospital treatment failure on third day (39.5% vs. 25.5.1%, p=0.137) and mortality rates (9% vs. 14.5%, p=0.401) were similar between HIV negative and HIV positive patients. CONCLUSION: Clinical and radiological features as well as response to treatment and in hospital fatal outcomes are similar in adult patients hospitalised with acute community-acquired pneumonia in Yaounde. In contrast, HIV infected patients tend to be more anaemic and have lower white cell counts than HIV negative patients. Larger prospective studies are needed to consolidate these findings. |
en_ZA |
dc.language.iso |
eng |
en_ZA |
dc.publisher |
BioMed Central Ltd |
en_ZA |
dc.rights |
This is an open access article distributed under the terms of the Creative Commons Attribution License |
en_ZA |
dc.rights.uri |
http://creativecommons.org/licenses/by/2.0 |
en_ZA |
dc.source |
BMC Pulmonary Medicine |
en_ZA |
dc.source.uri |
http://www.biomedcentral.com/bmcpulmmed/
|
en_ZA |
dc.subject.other |
Community-acquired pneumonia |
en_ZA |
dc.subject.other |
HIV infection |
en_ZA |
dc.subject.other |
Hospitalisation |
en_ZA |
dc.subject.other |
Outcomes |
en_ZA |
dc.subject.other |
Cameroon |
en_ZA |
dc.title |
Influence of HIV infection on the clinical presentation and outcome of adults with acute community-acquired pneumonia in Yaounde, Cameroon: a retrospective hospital-based study |
en_ZA |
dc.type |
Journal Article |
en_ZA |
dc.rights.holder |
2012 Pefura Yone et al.; licensee BioMed Central Ltd. |
en_ZA |
uct.type.publication |
Research |
en_ZA |
uct.type.resource |
Article
|
en_ZA |
dc.publisher.institution |
University of Cape Town |
|
dc.publisher.faculty |
Faculty of Health Sciences |
en_ZA |
dc.publisher.department |
Department of Medicine |
en_ZA |
uct.type.filetype |
Text |
|
uct.type.filetype |
Image |
|
dc.identifier.apacitation |
Yone, E. W., Balkissou, A., Kengne, A., & Kuaban, C. (2012). Influence of HIV infection on the clinical presentation and outcome of adults with acute community-acquired pneumonia in Yaounde, Cameroon: a retrospective hospital-based study. <i>BMC Pulmonary Medicine</i>, http://hdl.handle.net/11427/15657 |
en_ZA |
dc.identifier.chicagocitation |
Yone, Eric Walter, Adamou Balkissou, Andre Kengne, and Christopher Kuaban "Influence of HIV infection on the clinical presentation and outcome of adults with acute community-acquired pneumonia in Yaounde, Cameroon: a retrospective hospital-based study." <i>BMC Pulmonary Medicine</i> (2012) http://hdl.handle.net/11427/15657 |
en_ZA |
dc.identifier.vancouvercitation |
Yone EW, Balkissou A, Kengne A, Kuaban C. Influence of HIV infection on the clinical presentation and outcome of adults with acute community-acquired pneumonia in Yaounde, Cameroon: a retrospective hospital-based study. BMC Pulmonary Medicine. 2012; http://hdl.handle.net/11427/15657. |
en_ZA |
dc.identifier.ris |
TY - Journal Article
AU - Yone, Eric Walter
AU - Balkissou, Adamou
AU - Kengne, Andre
AU - Kuaban, Christopher
AB - BACKGROUND: The impact of HIV infection on the evolution of acute community-acquired pneumonia (CAP) is still controversial. The aim of this study was to investigate possible differences in the clinical presentation and in-hospital outcomes of patients with CAP with and without HIV infection in a specialised service in Yaounde. METHODS: Medical files of 106 patients (51 men) aged 15years and above, admitted to the Pneumology service of the Yaounde Jamot Hospital between January 2008 and May 2012, were retrospectively studied. RESULTS: Sixty-two (58.5%) patients were HIV infected. The median age of all patients was 40years (interquartile range: 31.75-53) and there was no difference in the clinical and radiological profile of patients with and without HIV infection. The median leukocyte count (interquartile range) was 14,600/mm3 (10,900-20,600) and 10,450/mm3 (6,400-16,850) respectively in HIV negative and HIV positive patients (p=0.002). Median haemoglobin level (interquartile range) was 10.8g/dl (8.9-12) in HIV negative and 9.7g/dl (8-11.6) in HIV positive patients (p=0.025). In-hospital treatment failure on third day (39.5% vs. 25.5.1%, p=0.137) and mortality rates (9% vs. 14.5%, p=0.401) were similar between HIV negative and HIV positive patients. CONCLUSION: Clinical and radiological features as well as response to treatment and in hospital fatal outcomes are similar in adult patients hospitalised with acute community-acquired pneumonia in Yaounde. In contrast, HIV infected patients tend to be more anaemic and have lower white cell counts than HIV negative patients. Larger prospective studies are needed to consolidate these findings.
DA - 2012
DB - OpenUCT
DO - 10.1186/1471-2466-12-46
DP - University of Cape Town
J1 - BMC Pulmonary Medicine
LK - https://open.uct.ac.za
PB - University of Cape Town
PY - 2012
T1 - Influence of HIV infection on the clinical presentation and outcome of adults with acute community-acquired pneumonia in Yaounde, Cameroon: a retrospective hospital-based study
TI - Influence of HIV infection on the clinical presentation and outcome of adults with acute community-acquired pneumonia in Yaounde, Cameroon: a retrospective hospital-based study
UR - http://hdl.handle.net/11427/15657
ER -
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en_ZA |