Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study

 

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dc.contributor.author Kaze, Francois en_ZA
dc.contributor.author Meto, Diane en_ZA
dc.contributor.author Halle, Marie-Patrice en_ZA
dc.contributor.author Ngogang, Jeanne en_ZA
dc.contributor.author Kengne, Andre-Pascal en_ZA
dc.date.accessioned 2015-12-07T08:52:07Z
dc.date.available 2015-12-07T08:52:07Z
dc.date.issued 2015 en_ZA
dc.identifier.citation Kaze, F. F., Meto, D. T., Halle, M. P., Ngogang, J., & Kengne, A. P. (2015). Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study. BMC nephrology, 16(1), 117. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/15648
dc.identifier.uri http://dx.doi.org/10.1186/s12882-015-0111-8
dc.description.abstract BACKGROUND: Chronic kidney disease (CKD) is a global public health problem that disproportionally affects people of African ethnicity. We assessed the prevalence and determinants of CKD and albuminuria in urban and rural adults Cameroonians. METHODS: This was a cross-sectional study of 6-month duration (February to July 2014), conducted in the health district of Dschang (Western Region of Cameroon), using a multistage cluster sampling. All adults diagnosed with albuminuria ([greater than or equal to]30mg/g) and/or decreased estimated glomerular filtration rate (eGFR) (<60ml/min/1.73m 2 ) were re-examined three months later. Logistic regression models were used to relate baseline characteristics with prevalent CKD. RESULTS: We included 439 participants with a mean age of 47+/-16.1years; with 185 (42.1%) being men and 119 (27.1%) being urban dwellers. There was a high prevalence of hypertension (25.5%), diabetes (9.8%), smoking (9.3%), alcohol consumption (59.7%), longstanding use of herbal medicine (90.9%) and street medications (87.5%), and overweight/obesity (53.3%) which were predominant in rural area. The prevalence of CKD was 13.2% overall, 14.1% in rural and 10.9% in urban participants. Equivalents figures for CKD stages G3-G4 and albuminuria were 2.5%, 1.6% and 5.0%; and 12.1%, 14.1% and 6.7% respectively. Existing hypertension and diabetes were associated with all outcomes. Elevated systolic blood pressure and the presence of hypertension and diabetes were the predictors of albuminuria and CKD while urban residence was associated with CKD stages G3-G4. CONCLUSION: The prevalence of CKD and albuminuria was high in this population, predominantly in rural area, and driven mostly by the commonest risk factors. en_ZA
dc.language.iso eng en_ZA
dc.publisher BioMed Central Ltd en_ZA
dc.rights This is an Open Access article distributed under the terms of the Creative Commons Attribution License en_ZA
dc.rights.uri http://creativecommons.org/licenses/by/4.0 en_ZA
dc.source BMC Nephrology en_ZA
dc.source.uri http://www.biomedcentral.com/bmcnephrol/ en_ZA
dc.subject.other Chronic kidney disease (CKD) en_ZA
dc.subject.other albuminuria en_ZA
dc.title Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study en_ZA
dc.type Journal Article en_ZA
dc.rights.holder 2015 Kaze et al. en_ZA
uct.type.publication Research en_ZA
uct.type.resource Article en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Medicine en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Kaze, F., Meto, D., Halle, M., Ngogang, J., & Kengne, A. (2015). Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study. <i>BMC Nephrology</i>, http://hdl.handle.net/11427/15648 en_ZA
dc.identifier.chicagocitation Kaze, Francois, Diane Meto, Marie-Patrice Halle, Jeanne Ngogang, and Andre-Pascal Kengne "Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study." <i>BMC Nephrology</i> (2015) http://hdl.handle.net/11427/15648 en_ZA
dc.identifier.vancouvercitation Kaze F, Meto D, Halle M, Ngogang J, Kengne A. Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study. BMC Nephrology. 2015; http://hdl.handle.net/11427/15648. en_ZA
dc.identifier.ris TY - Journal Article AU - Kaze, Francois AU - Meto, Diane AU - Halle, Marie-Patrice AU - Ngogang, Jeanne AU - Kengne, Andre-Pascal AB - BACKGROUND: Chronic kidney disease (CKD) is a global public health problem that disproportionally affects people of African ethnicity. We assessed the prevalence and determinants of CKD and albuminuria in urban and rural adults Cameroonians. METHODS: This was a cross-sectional study of 6-month duration (February to July 2014), conducted in the health district of Dschang (Western Region of Cameroon), using a multistage cluster sampling. All adults diagnosed with albuminuria ([greater than or equal to]30mg/g) and/or decreased estimated glomerular filtration rate (eGFR) (<60ml/min/1.73m 2 ) were re-examined three months later. Logistic regression models were used to relate baseline characteristics with prevalent CKD. RESULTS: We included 439 participants with a mean age of 47+/-16.1years; with 185 (42.1%) being men and 119 (27.1%) being urban dwellers. There was a high prevalence of hypertension (25.5%), diabetes (9.8%), smoking (9.3%), alcohol consumption (59.7%), longstanding use of herbal medicine (90.9%) and street medications (87.5%), and overweight/obesity (53.3%) which were predominant in rural area. The prevalence of CKD was 13.2% overall, 14.1% in rural and 10.9% in urban participants. Equivalents figures for CKD stages G3-G4 and albuminuria were 2.5%, 1.6% and 5.0%; and 12.1%, 14.1% and 6.7% respectively. Existing hypertension and diabetes were associated with all outcomes. Elevated systolic blood pressure and the presence of hypertension and diabetes were the predictors of albuminuria and CKD while urban residence was associated with CKD stages G3-G4. CONCLUSION: The prevalence of CKD and albuminuria was high in this population, predominantly in rural area, and driven mostly by the commonest risk factors. DA - 2015 DB - OpenUCT DO - 10.1186/s12882-015-0111-8 DP - University of Cape Town J1 - BMC Nephrology LK - https://open.uct.ac.za PB - University of Cape Town PY - 2015 T1 - Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study TI - Prevalence and determinants of chronic kidney disease in rural and urban Cameroonians: a cross-sectional study UR - http://hdl.handle.net/11427/15648 ER - en_ZA


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