Genomic medicine in Africa: promise, problems and prospects

 

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dc.contributor.author Wonkam, Ambroise en_ZA
dc.contributor.author Mayosi, Bongani en_ZA
dc.date.accessioned 2015-11-27T09:33:41Z
dc.date.available 2015-11-27T09:33:41Z
dc.date.issued 2014 en_ZA
dc.identifier.citation Wonkam, A., & Mayosi, B. M. (2014). Genomic medicine in Africa: promise, problems and prospects. Genome medicine, 6(2), 11. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/15401
dc.identifier.uri http://dx.doi.org/10.1186/gm528
dc.description.abstract Remarkable progress has been made in using genomic information to determine how genes are regulated, and how they interact with each other and with the environment to control complex biochemical functions of living organisms in health and disease [1]. This information will have major benefits for the prevention, diagnosis and management of many diseases, including communicable and genetic diseases. In Africa, where infectious diseases are highly prevalent, research on pathogen genomes has enhanced our understanding of disease transmission, virulence mechanisms and avoidance of host defenses [2]. It is anticipated that this information will enable the development of new diagnostic tests, vaccines and therapeutic agents; it is also likely to lead to new approaches for vector control, and reveal why individuals and populations vary in their susceptibility to infectious diseases [1]. en_ZA
dc.language.iso eng en_ZA
dc.publisher BioMed Central Ltd en_ZA
dc.rights This article is available under the terms of the Creative Commons Attribution License en_ZA
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en_ZA
dc.source Genome Medicine en_ZA
dc.source.uri http://www.genomemedicine.com/ en_ZA
dc.subject.other genomic information en_ZA
dc.subject.other genes regulation en_ZA
dc.subject.other genes interaction en_ZA
dc.subject.other biochemical functions en_ZA
dc.subject.other living organisms en_ZA
dc.subject.other health en_ZA
dc.subject.other disease en_ZA
dc.title Genomic medicine in Africa: promise, problems and prospects en_ZA
dc.type Journal Article en_ZA
dc.rights.holder 2014 Wonkam and Mayosi; licensee BioMed Central Ltd. en_ZA
uct.type.publication Research en_ZA
uct.type.resource Article en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Medicine en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Wonkam, A., & Mayosi, B. (2014). Genomic medicine in Africa: promise, problems and prospects. <i>Genome Medicine</i>, http://hdl.handle.net/11427/15401 en_ZA
dc.identifier.chicagocitation Wonkam, Ambroise, and Bongani Mayosi "Genomic medicine in Africa: promise, problems and prospects." <i>Genome Medicine</i> (2014) http://hdl.handle.net/11427/15401 en_ZA
dc.identifier.vancouvercitation Wonkam A, Mayosi B. Genomic medicine in Africa: promise, problems and prospects. Genome Medicine. 2014; http://hdl.handle.net/11427/15401. en_ZA
dc.identifier.ris TY - Journal Article AU - Wonkam, Ambroise AU - Mayosi, Bongani AB - Remarkable progress has been made in using genomic information to determine how genes are regulated, and how they interact with each other and with the environment to control complex biochemical functions of living organisms in health and disease [1]. This information will have major benefits for the prevention, diagnosis and management of many diseases, including communicable and genetic diseases. In Africa, where infectious diseases are highly prevalent, research on pathogen genomes has enhanced our understanding of disease transmission, virulence mechanisms and avoidance of host defenses [2]. It is anticipated that this information will enable the development of new diagnostic tests, vaccines and therapeutic agents; it is also likely to lead to new approaches for vector control, and reveal why individuals and populations vary in their susceptibility to infectious diseases [1]. DA - 2014 DB - OpenUCT DO - 10.1186/gm528 DP - University of Cape Town J1 - Genome Medicine LK - https://open.uct.ac.za PB - University of Cape Town PY - 2014 T1 - Genomic medicine in Africa: promise, problems and prospects TI - Genomic medicine in Africa: promise, problems and prospects UR - http://hdl.handle.net/11427/15401 ER - en_ZA


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