Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study

 

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dc.contributor.author Pefura-Yone, Eric en_ZA
dc.contributor.author Kengne, Andre en_ZA
dc.contributor.author Afane-Ze, Emmanuel en_ZA
dc.contributor.author Kuaban, Christopher en_ZA
dc.date.accessioned 2015-11-27T09:33:35Z
dc.date.available 2015-11-27T09:33:35Z
dc.date.issued 2014 en_ZA
dc.identifier.citation Pefura-Yone, E. W., Kengne, A. P., Afane-Ze, E., & Kuaban, C. (2014). Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study. World Allergy Organization Journal, 7(1), 22. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/15395
dc.identifier.uri http://dx.doi.org/10.1186/1939-4551-7-22
dc.description.abstract BACKGROUND: German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not received attention. The aim of this study was to assess the prevalence and investigate the predicting factors of sensitisation to Blattella germanica in patients with asthma in Yaounde, Cameroon. METHODS: This was a cross-sectional study conducted between January 2012 and June 2013. All patients (aged 15years and above) with asthma, receiving care at the Yaounde Jamot Hospital and the CEDIMER medical practice during the study period and who had received a prick skin testing for perennial aeroallergens were included in the study. RESULTS: The final sample comprised 184 patients including 123 (66.8%) women. The median age (25th-75th percentiles) was 38 (24-54) years. Prick skin test for Blattella germanica was positive in 47 (25.5%) patients. Sensitisation to Blattella germanica was associated with a sensitisation to mite in 41 (87.2%) patients, a sensitisation to Alternaria in 18 (38.3%) patients, and a sensitisation to cat or dog dander in 7 (14.9%) patients. Independent predicting factors of a sensitisation to Blattella germanica were the sensitisation to Blomia tropicalis [adjusted odd ratio (95% confidence interval) 4.10 (1.67-10.04), p=0.002] and sensitisation to Alternaria [3.67 (1.53-7.46), p=0.003]. CONCLUSIONS: Sensitisation to Blattella germanica is present in about a quarter of adult patients with asthma in Yaounde. Sensitisation to Alternaria and Blomia tropicalis appears to be a powerful predicting factor of sensitisation to Blattella germanica in this setting. en_ZA
dc.language.iso eng en_ZA
dc.publisher BioMed Central Ltd en_ZA
dc.rights This is an Open Access article distributed under the terms of the Creative Commons Attribution License en_ZA
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en_ZA
dc.source World Allergy Organization Journal en_ZA
dc.source.uri http://www.waojournal.org/ en_ZA
dc.subject.other Asthma en_ZA
dc.subject.other Blattella en_ZA
dc.subject.other Allergy en_ZA
dc.subject.other Aeroallergens en_ZA
dc.subject.other Africa en_ZA
dc.title Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study en_ZA
dc.type Journal Article en_ZA
dc.rights.holder 2014 Pefura-Yone et al.; licensee BioMed Central Ltd. en_ZA
uct.type.publication Research en_ZA
uct.type.resource Article en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Medicine en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Pefura-Yone, E., Kengne, A., Afane-Ze, E., & Kuaban, C. (2014). Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study. <i>World Allergy Organization Journal</i>, http://hdl.handle.net/11427/15395 en_ZA
dc.identifier.chicagocitation Pefura-Yone, Eric, Andre Kengne, Emmanuel Afane-Ze, and Christopher Kuaban "Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study." <i>World Allergy Organization Journal</i> (2014) http://hdl.handle.net/11427/15395 en_ZA
dc.identifier.vancouvercitation Pefura-Yone E, Kengne A, Afane-Ze E, Kuaban C. Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study. World Allergy Organization Journal. 2014; http://hdl.handle.net/11427/15395. en_ZA
dc.identifier.ris TY - Journal Article AU - Pefura-Yone, Eric AU - Kengne, Andre AU - Afane-Ze, Emmanuel AU - Kuaban, Christopher AB - BACKGROUND: German cockroach or Blattella germanica is commonly found in homes across the inter-tropical region. The contribution of sensitisation to Blattella germanica in people with asthma in sub-Saharan Africa has not received attention. The aim of this study was to assess the prevalence and investigate the predicting factors of sensitisation to Blattella germanica in patients with asthma in Yaounde, Cameroon. METHODS: This was a cross-sectional study conducted between January 2012 and June 2013. All patients (aged 15years and above) with asthma, receiving care at the Yaounde Jamot Hospital and the CEDIMER medical practice during the study period and who had received a prick skin testing for perennial aeroallergens were included in the study. RESULTS: The final sample comprised 184 patients including 123 (66.8%) women. The median age (25th-75th percentiles) was 38 (24-54) years. Prick skin test for Blattella germanica was positive in 47 (25.5%) patients. Sensitisation to Blattella germanica was associated with a sensitisation to mite in 41 (87.2%) patients, a sensitisation to Alternaria in 18 (38.3%) patients, and a sensitisation to cat or dog dander in 7 (14.9%) patients. Independent predicting factors of a sensitisation to Blattella germanica were the sensitisation to Blomia tropicalis [adjusted odd ratio (95% confidence interval) 4.10 (1.67-10.04), p=0.002] and sensitisation to Alternaria [3.67 (1.53-7.46), p=0.003]. CONCLUSIONS: Sensitisation to Blattella germanica is present in about a quarter of adult patients with asthma in Yaounde. Sensitisation to Alternaria and Blomia tropicalis appears to be a powerful predicting factor of sensitisation to Blattella germanica in this setting. DA - 2014 DB - OpenUCT DO - 10.1186/1939-4551-7-22 DP - University of Cape Town J1 - World Allergy Organization Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2014 T1 - Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study TI - Sensitisation to Blattella germanica among adults with asthma in Yaounde, Cameroon: a cross-sectional study UR - http://hdl.handle.net/11427/15395 ER - en_ZA


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