dc.contributor.author |
Machingaidze, Shingai
|
en_ZA |
dc.contributor.author |
Rehfuess, Eva
|
en_ZA |
dc.contributor.author |
von Kries, Rudiger
|
en_ZA |
dc.contributor.author |
Hussey, Gregory
|
en_ZA |
dc.contributor.author |
Wiysonge, Charles
|
en_ZA |
dc.date.accessioned |
2015-11-23T11:44:12Z |
|
dc.date.available |
2015-11-23T11:44:12Z |
|
dc.date.issued |
2013 |
en_ZA |
dc.identifier.citation |
Machingaidze, S., Rehfuess, E., von Kries, R., Hussey, G. D., & Wiysonge, C. S. (2013). Understanding interventions for improving routine immunization coverage in children in low-and middle-income countries: a systematic review protocol. Systematic reviews, 2(1), 106. |
en_ZA |
dc.identifier.uri |
http://hdl.handle.net/11427/15242
|
|
dc.identifier.uri |
http://dx.doi.org/10.1186/2046-4053-2-106
|
|
dc.description.abstract |
BACKGROUND: Virtually all low- and middle-income countries are dependent on the World Health Organization's Expanded Program on Immunization for delivery of vaccines to children. The Expanded Program on Immunization delivers routine immunization services from health facilities free of charge. Understanding interventions for improving immunization coverage remains key in achieving universal childhood immunization. METHODS: We will conduct a systematic review that aims to assess the effectiveness of the full range of potential interventions to improve routine immunization coverage in children in low- and middle-income countries. We will include intervention studies, as well as observational studies. We will search the Cochrane Database of Systematic Reviews (CDSR), Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, electronic databases for eligible studies published by 31 August 2013. At least two authors will independently screen search outputs, select studies, extract data and assess the risk of bias (using separate criteria for interventions and observational studies); resolving any disagreements by discussion and consensus. The use of logic models and the Cochrane Complexity Matrix will be explored in order to better understand and contextualize studies. We will express the result of each study as a risk ratio with its corresponding 95% confidence intervals for dichotomous data, or mean difference with its standard deviation for continuous data. We will conduct meta-analysis for the same type of participants, interventions, study designs, and outcome measures where homogeneity of data allows. Use of harvest plots may be explored as an alternative. Heterogeneity will be assessed using the chi2 test of heterogeneity, and quantified using the I2 statistic. This protocol has not been registered with PROSPERO.DISCUSSION:This review will allow us to document evidence across a broad range of intervention types for improving routine immunization coverage in children and also distinguish between those that are well supported by evidence (to direct policy recommendations) and those that are not well supported (to direct research agenda). |
en_ZA |
dc.language.iso |
eng |
en_ZA |
dc.publisher |
BioMed Central Ltd |
en_ZA |
dc.rights |
This is an Open Access article distributed under the terms of the Creative Commons Attribution License |
en_ZA |
dc.rights.uri |
http://creativecommons.org/licenses/by/2.0 |
en_ZA |
dc.source |
Systematic Reviews |
en_ZA |
dc.source.uri |
http://www.systematicreviewsjournal.com/
|
en_ZA |
dc.subject.other |
Expanded Program on Immunization (EPI) |
en_ZA |
dc.subject.other |
Routine immunization |
en_ZA |
dc.subject.other |
Routine vaccination |
en_ZA |
dc.subject.other |
Children |
en_ZA |
dc.subject.other |
Low- and middle-income countries |
en_ZA |
dc.title |
Understanding interventions for improving routine immunization coverage in children in low- and middle-income countries: a systematic review protocol |
en_ZA |
dc.type |
Journal Article |
en_ZA |
dc.rights.holder |
2013 Machingaidze et al.; licensee BioMed Central Ltd. |
en_ZA |
uct.type.publication |
Research |
en_ZA |
uct.type.resource |
Article
|
en_ZA |
dc.publisher.institution |
University of Cape Town |
|
dc.publisher.faculty |
Faculty of Health Sciences |
en_ZA |
dc.publisher.department |
Institute of Infectious Disease and Molecular Medicine |
en_ZA |
uct.type.filetype |
Text |
|
uct.type.filetype |
Image |
|
dc.identifier.apacitation |
Machingaidze, S., Rehfuess, E., von Kries, R., Hussey, G., & Wiysonge, C. (2013). Understanding interventions for improving routine immunization coverage in children in low- and middle-income countries: a systematic review protocol. <i>Systematic Reviews</i>, http://hdl.handle.net/11427/15242 |
en_ZA |
dc.identifier.chicagocitation |
Machingaidze, Shingai, Eva Rehfuess, Rudiger von Kries, Gregory Hussey, and Charles Wiysonge "Understanding interventions for improving routine immunization coverage in children in low- and middle-income countries: a systematic review protocol." <i>Systematic Reviews</i> (2013) http://hdl.handle.net/11427/15242 |
en_ZA |
dc.identifier.vancouvercitation |
Machingaidze S, Rehfuess E, von Kries R, Hussey G, Wiysonge C. Understanding interventions for improving routine immunization coverage in children in low- and middle-income countries: a systematic review protocol. Systematic Reviews. 2013; http://hdl.handle.net/11427/15242. |
en_ZA |
dc.identifier.ris |
TY - Journal Article
AU - Machingaidze, Shingai
AU - Rehfuess, Eva
AU - von Kries, Rudiger
AU - Hussey, Gregory
AU - Wiysonge, Charles
AB - BACKGROUND: Virtually all low- and middle-income countries are dependent on the World Health Organization's Expanded Program on Immunization for delivery of vaccines to children. The Expanded Program on Immunization delivers routine immunization services from health facilities free of charge. Understanding interventions for improving immunization coverage remains key in achieving universal childhood immunization. METHODS: We will conduct a systematic review that aims to assess the effectiveness of the full range of potential interventions to improve routine immunization coverage in children in low- and middle-income countries. We will include intervention studies, as well as observational studies. We will search the Cochrane Database of Systematic Reviews (CDSR), Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, electronic databases for eligible studies published by 31 August 2013. At least two authors will independently screen search outputs, select studies, extract data and assess the risk of bias (using separate criteria for interventions and observational studies); resolving any disagreements by discussion and consensus. The use of logic models and the Cochrane Complexity Matrix will be explored in order to better understand and contextualize studies. We will express the result of each study as a risk ratio with its corresponding 95% confidence intervals for dichotomous data, or mean difference with its standard deviation for continuous data. We will conduct meta-analysis for the same type of participants, interventions, study designs, and outcome measures where homogeneity of data allows. Use of harvest plots may be explored as an alternative. Heterogeneity will be assessed using the chi2 test of heterogeneity, and quantified using the I2 statistic. This protocol has not been registered with PROSPERO.DISCUSSION:This review will allow us to document evidence across a broad range of intervention types for improving routine immunization coverage in children and also distinguish between those that are well supported by evidence (to direct policy recommendations) and those that are not well supported (to direct research agenda).
DA - 2013
DB - OpenUCT
DO - 10.1186/2046-4053-2-106
DP - University of Cape Town
J1 - Systematic Reviews
LK - https://open.uct.ac.za
PB - University of Cape Town
PY - 2013
T1 - Understanding interventions for improving routine immunization coverage in children in low- and middle-income countries: a systematic review protocol
TI - Understanding interventions for improving routine immunization coverage in children in low- and middle-income countries: a systematic review protocol
UR - http://hdl.handle.net/11427/15242
ER -
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en_ZA |