A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques

 

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dc.contributor.author Chege, GK en_ZA
dc.contributor.author Chapman, R en_ZA
dc.contributor.author Shephard, EG en_ZA
dc.contributor.author Williamson, A en_ZA
dc.date.accessioned 2015-11-18T03:47:00Z
dc.date.available 2015-11-18T03:47:00Z
dc.date.issued 2012 en_ZA
dc.identifier.citation Chege, G. K., Chapman, R., Shephard, E. G., & Williamson, A. (2012). A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques. Retrovirology, 9(Suppl 2), P40. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/15047
dc.identifier.uri http://dx.doi.org/10.1186/1742-4690-9-S2-P40
dc.description.abstract CG pantothenate auxtroph (ΔpanCD) is safer to use as a live vaccine vector than wild-type BCG. We constructed 3 recombinant BCGΔpanCD candidate vaccines expressing HIV-1 subtype C Gag, RT and Env (gp120). The current study investigated immune responses in rhesus macaques following a prime with a mixture of these rBCG vaccines and a boost with SAAVI MVA-C (MVA). en_ZA
dc.language.iso eng en_ZA
dc.publisher BioMed Central Ltd en_ZA
dc.rights This is an Open Access article distributed under the terms of the Creative Commons Attribution License en_ZA
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en_ZA
dc.source Retrovirology en_ZA
dc.source.uri http://www.retrovirology.com/ en_ZA
dc.subject.other HIV-1 Peptide en_ZA
dc.subject.other HIV-1 Subtype en_ZA
dc.subject.other rBCG Vaccine en_ZA
dc.subject.other vaccine-specific Immune Response en_ZA
dc.title A prime-boost immunization with rBCG expressing HIV-1 Gag, RT and gp120 and SAAVI MVA-C elicits immune responses in blood and MALT of rhesus macaques en_ZA
dc.type Journal Article en_ZA
dc.rights.holder 2012 Chege et al; licensee BioMed Central Ltd. en_ZA
uct.type.publication Research en_ZA
uct.type.resource Article en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Division of Virology en_ZA
uct.type.filetype Text
uct.type.filetype Image


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This is an Open Access article distributed under the terms of the Creative Commons Attribution License Except where otherwise noted, this item's license is described as This is an Open Access article distributed under the terms of the Creative Commons Attribution License