Quantifying right ventricular motion and strain using 3D cine DENSE MRI

 

Show simple item record

dc.contributor.author Auger, Daniel en_ZA
dc.contributor.author Zhong, Xiaodong en_ZA
dc.contributor.author Meintjes, Ernesta M en_ZA
dc.contributor.author Epstein, Frederick H en_ZA
dc.contributor.author Spottiswoode, Bruce S en_ZA
dc.date.accessioned 2015-11-11T12:01:16Z
dc.date.available 2015-11-11T12:01:16Z
dc.date.issued 2011 en_ZA
dc.identifier.citation Auger, D. A., Zhong, X., Meintjes, E. M., Epstein, F. H., & Spottiswoode, B. S. (2011). Quantifying right ventricular motion and strain using 3D cine DENSE MRI. Journal of Cardiovascular Magnetic Resonance, 13(1), 1-2. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/14887
dc.identifier.uri http://dx.doi.org/10.1186/1532-429X-13-S1-M3
dc.description.abstract Background: The RV is difficult to image because of its thin wall, asymmetric geometry and complex motion. DENSE is a quantitative MRI technique for measuring myocardial displacement and strain at high spatial and temporal resolutions [1,2]. DENSE encodes tissue displacement directly into the image phase, allowing for the direct extraction of motion data at a pixel resolution. A free-breathing navigator-gated spiral 3D cine DENSE sequence was recently developed [3], providing an MRI technique which is well suited to quantifying RV mechanics. Methods: Whole heart 3D cine DENSE data were acquired from two normal volunteers, after informed consent was obtained and in accordance with protocols approved by the University of Virginia institutional review board. The endocardial and epicardial contours were manually delineated to identify the myocardium from surrounding anatomical structures. A 3D spatiotemporal phase unwrapping algorithm was used to remove phase aliasing [4], and 3D Lagrangian displacement fields were derived for all cardiac phases. Midline contours were calculated from the epicardial and endocardial contours, and tissue tracking seed points were defined at pixel spaced intervals. A 3D tracking algorithm was implemented as a direct extension of the 2D tracking algorithm presented in [4], producing midline motion trajectories from which strain was calculated. Tangential 1D strain was calculated in the longitudinal and circumferential cardiac directions. Strain time curves are computed representing the free wall of the RV. Results: Figure 1 illustrates the RV free wall mean tangential 1D strain time curves for approximately 3/4 of the cardiac cycle over the apical-mid section of the heart for one volunteer. Results show measurements ranging between -0.1 and -0.25, and further illustrate a greater displacement in the longitudinal direction. Results compare favorably with studies using myocardial tagging and DENSE[5,6]. en_ZA
dc.language.iso eng en_ZA
dc.publisher BioMed Central Ltd en_ZA
dc.rights This is an Open Access article distributed under the terms of the Creative Commons Attribution License en_ZA
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en_ZA
dc.source Journal of Cardiovascular Magnetic Resonance en_ZA
dc.source.uri http://www.jcmr-online.com/ en_ZA
dc.subject.other Cine Dense en_ZA
dc.subject.other Tissue Tracking en_ZA
dc.subject.other Dense MRI en_ZA
dc.subject.other Tracking Algorithm en_ZA
dc.subject.other Motion Trajectory en_ZA
dc.subject.other Myocardial Displacement en_ZA
dc.subject.other 3d Cine en_ZA
dc.subject.other Spatiotemporal Phase en_ZA
dc.subject.other RV Mechanic en_ZA
dc.subject.other Lagrangian Displacement en_ZA
dc.title Quantifying right ventricular motion and strain using 3D cine DENSE MRI en_ZA
dc.type Journal Article en_ZA
dc.rights.holder 2011 Auger et al; licensee BioMed Central Ltd. en_ZA
uct.type.publication Research en_ZA
uct.type.resource Article en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Human Biology en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Auger, D., Zhong, X., Meintjes, E. M., Epstein, F. H., & Spottiswoode, B. S. (2011). Quantifying right ventricular motion and strain using 3D cine DENSE MRI. <i>Journal of Cardiovascular Magnetic Resonance</i>, http://hdl.handle.net/11427/14887 en_ZA
dc.identifier.chicagocitation Auger, Daniel, Xiaodong Zhong, Ernesta M Meintjes, Frederick H Epstein, and Bruce S Spottiswoode "Quantifying right ventricular motion and strain using 3D cine DENSE MRI." <i>Journal of Cardiovascular Magnetic Resonance</i> (2011) http://hdl.handle.net/11427/14887 en_ZA
dc.identifier.vancouvercitation Auger D, Zhong X, Meintjes EM, Epstein FH, Spottiswoode BS. Quantifying right ventricular motion and strain using 3D cine DENSE MRI. Journal of Cardiovascular Magnetic Resonance. 2011; http://hdl.handle.net/11427/14887. en_ZA
dc.identifier.ris TY - Journal Article AU - Auger, Daniel AU - Zhong, Xiaodong AU - Meintjes, Ernesta M AU - Epstein, Frederick H AU - Spottiswoode, Bruce S AB - Background: The RV is difficult to image because of its thin wall, asymmetric geometry and complex motion. DENSE is a quantitative MRI technique for measuring myocardial displacement and strain at high spatial and temporal resolutions [1,2]. DENSE encodes tissue displacement directly into the image phase, allowing for the direct extraction of motion data at a pixel resolution. A free-breathing navigator-gated spiral 3D cine DENSE sequence was recently developed [3], providing an MRI technique which is well suited to quantifying RV mechanics. Methods: Whole heart 3D cine DENSE data were acquired from two normal volunteers, after informed consent was obtained and in accordance with protocols approved by the University of Virginia institutional review board. The endocardial and epicardial contours were manually delineated to identify the myocardium from surrounding anatomical structures. A 3D spatiotemporal phase unwrapping algorithm was used to remove phase aliasing [4], and 3D Lagrangian displacement fields were derived for all cardiac phases. Midline contours were calculated from the epicardial and endocardial contours, and tissue tracking seed points were defined at pixel spaced intervals. A 3D tracking algorithm was implemented as a direct extension of the 2D tracking algorithm presented in [4], producing midline motion trajectories from which strain was calculated. Tangential 1D strain was calculated in the longitudinal and circumferential cardiac directions. Strain time curves are computed representing the free wall of the RV. Results: Figure 1 illustrates the RV free wall mean tangential 1D strain time curves for approximately 3/4 of the cardiac cycle over the apical-mid section of the heart for one volunteer. Results show measurements ranging between -0.1 and -0.25, and further illustrate a greater displacement in the longitudinal direction. Results compare favorably with studies using myocardial tagging and DENSE[5,6]. DA - 2011 DB - OpenUCT DO - 10.1186/1532-429X-13-S1-M3 DP - University of Cape Town J1 - Journal of Cardiovascular Magnetic Resonance LK - https://open.uct.ac.za PB - University of Cape Town PY - 2011 T1 - Quantifying right ventricular motion and strain using 3D cine DENSE MRI TI - Quantifying right ventricular motion and strain using 3D cine DENSE MRI UR - http://hdl.handle.net/11427/14887 ER - en_ZA


Files in this item

This item appears in the following Collection(s)

Show simple item record

This is an Open Access article distributed under the terms of the Creative Commons Attribution License Except where otherwise noted, this item's license is described as This is an Open Access article distributed under the terms of the Creative Commons Attribution License