Virtual reality exposure therapy as treatment for pain catastrophizing in fibromyalgia patients: proof-of-concept study (Study Protocol)

 

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dc.contributor.author Morris, Linzette en_ZA
dc.contributor.author Grimmer-Somers, Karen en_ZA
dc.contributor.author Spottiswoode, Bruce en_ZA
dc.contributor.author Louw, Quinette en_ZA
dc.date.accessioned 2015-11-11T11:52:15Z
dc.date.available 2015-11-11T11:52:15Z
dc.date.issued 2011 en_ZA
dc.identifier.citation Morris, L. D., Grimmer-Somers, K. A., Spottiswoode, B., & Louw, Q. A. (2011). Virtual reality exposure therapy as treatment for pain catastrophizing in fibromyalgia patients: proof-of-concept study (Study Protocol). BMC Musculoskeletal Disorders, 12(1), 85. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/14851
dc.identifier.uri http://dx.doi.org/10.1186/1471-2474-12-85
dc.description.abstract BACKGROUND: Albeit exercise is currently advocated as one of the most effective management strategies for fibromyalgia syndrome (FMS); the implementation of exercise as a FMS treatment in reality is significantly hampered by patients' poor compliance. The inference that pain catastrophizing is a key predictor of poor compliance in FMS patients, justifies considering the alteration of pain catastrophizing in improving compliance towards exercises in FMS patients. The aim of this study is to provide proof-of-concept for the development and testing of a novel virtual reality exposure therapy (VRET) program as treatment for exercise-related pain catastrophizing in FMS patients. METHODS: Two interlinked experimental studies will be conducted. Study 1 aims to objectively ascertain if neurophysiological changes occur in the functional brain areas associated with pain catastrophizing, when catastrophizing FMS subjects are exposed to visuals of exercise activities. Study 2 aims to ascertain the preliminary efficacy and feasibility of exposure to visuals of exercise activities as a treatment for exercise-related pain catastrophizing in FMS subjects. Twenty subjects will be selected from a group of FMS patients attending the Tygerberg Hospital in Cape Town, South Africa and randomly allocated to either the VRET (intervention) group or waiting list (control) group. Baseline neurophysiological activity for subjects will be collected in study 1 using functional magnetic resonance imaging (fMRI). In study 2, clinical improvement in pain catastrophizing will be measured using fMRI (objective) and the pain catastrophizing scale (subjective).DISCUSSION:The premise is if exposing FMS patients to visuals of various exercise activities trigger the functional brain areas associated with pain catastrophizing; then as a treatment, repeated exposure to visuals of the exercise activities using a VRET program could possibly decrease exercise-related pain catastrophizing in FMS patients. Proof-of-concept will either be established or negated. The results of this project are envisaged to revolutionize FMS and pain catastrophizing research and in the future, assist health professionals and FMS patients in reducing despondency regarding FMS management.TRIAL REGISTRATION:PACTR201011000264179 en_ZA
dc.language.iso eng en_ZA
dc.publisher BioMed Central Ltd en_ZA
dc.rights This is an Open Access article distributed under the terms of the Creative Commons Attribution License en_ZA
dc.rights.uri http://creativecommons.org/licenses/by/2.0 en_ZA
dc.source BMC Musculoskeletal Disorders en_ZA
dc.source.uri http://www.biomedcentral.com/bmcmusculoskeletdisord/ en_ZA
dc.subject.other fibromyalgia syndrome en_ZA
dc.subject.other pain catastrophizing en_ZA
dc.subject.other virtual reality exposure therapy en_ZA
dc.subject.other exercise and compliance en_ZA
dc.title Virtual reality exposure therapy as treatment for pain catastrophizing in fibromyalgia patients: proof-of-concept study (Study Protocol) en_ZA
dc.type Journal Article en_ZA
dc.rights.holder 2011 Morris et al; licensee BioMed Central Ltd. en_ZA
uct.type.publication Research en_ZA
uct.type.resource Article en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department MRC/UCT Medical Imaging Research Unit en_ZA
uct.type.filetype Text
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License Except where otherwise noted, this item's license is described as This is an Open Access article distributed under the terms of the Creative Commons Attribution License