The relationship between neurocognitive disorders, prospective memory impairment and white matter damage in clade C HIV-positive subjects

 

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dc.contributor.advisor Joska, John Anton en_ZA
dc.contributor.advisor Stein, Dan J en_ZA
dc.contributor.author Hoare, Jacqueline en_ZA
dc.date.accessioned 2015-11-08T05:04:52Z
dc.date.available 2015-11-08T05:04:52Z
dc.date.issued 2010 en_ZA
dc.identifier.citation Hoare, J. 2010. The relationship between neurocognitive disorders, prospective memory impairment and white matter damage in clade C HIV-positive subjects. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/14734
dc.description Includes bibliographical references. en_ZA
dc.description.abstract AIMS: To examine the relationship between prospective memory, cognitive function and Diffusion tensor imaging (DTI)/ White matter integrity of human immunodeficiency virus (HIV) positive individuals in the Western Cape. We hypothesize that: 1. Individuals infected with HIV will exhibit significantly poorer microstructural integrity of the white matter than HIV negative individuals, as determined by in vivo diffusion tensor imaging. We expect that values of fractional anisotropy (FA) - a measure of directional water diffusion- in the frontal white matter will be significantly lower among HIV patients compared to controls 2. Lower FA measured in the frontal white matter will correlate significantly with impaired performance on tests of prospective memory en_ZA
dc.language.iso eng en_ZA
dc.subject.other Neuropsychiatry en_ZA
dc.title The relationship between neurocognitive disorders, prospective memory impairment and white matter damage in clade C HIV-positive subjects en_ZA
dc.type Master Thesis
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Division of Neuropsychiatry en_ZA
dc.type.qualificationlevel Masters
dc.type.qualificationname MPhil en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Hoare, J. (2010). <i>The relationship between neurocognitive disorders, prospective memory impairment and white matter damage in clade C HIV-positive subjects</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Neuropsychiatry. Retrieved from http://hdl.handle.net/11427/14734 en_ZA
dc.identifier.chicagocitation Hoare, Jacqueline. <i>"The relationship between neurocognitive disorders, prospective memory impairment and white matter damage in clade C HIV-positive subjects."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Neuropsychiatry, 2010. http://hdl.handle.net/11427/14734 en_ZA
dc.identifier.vancouvercitation Hoare J. The relationship between neurocognitive disorders, prospective memory impairment and white matter damage in clade C HIV-positive subjects. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Neuropsychiatry, 2010 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/14734 en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Hoare, Jacqueline AB - AIMS: To examine the relationship between prospective memory, cognitive function and Diffusion tensor imaging (DTI)/ White matter integrity of human immunodeficiency virus (HIV) positive individuals in the Western Cape. We hypothesize that: 1. Individuals infected with HIV will exhibit significantly poorer microstructural integrity of the white matter than HIV negative individuals, as determined by in vivo diffusion tensor imaging. We expect that values of fractional anisotropy (FA) - a measure of directional water diffusion- in the frontal white matter will be significantly lower among HIV patients compared to controls 2. Lower FA measured in the frontal white matter will correlate significantly with impaired performance on tests of prospective memory DA - 2010 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2010 T1 - The relationship between neurocognitive disorders, prospective memory impairment and white matter damage in clade C HIV-positive subjects TI - The relationship between neurocognitive disorders, prospective memory impairment and white matter damage in clade C HIV-positive subjects UR - http://hdl.handle.net/11427/14734 ER - en_ZA


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