Dimethyl N-Aryl phosphoramidates : structural effects on bonding and solvolytic reactivity

Rijkmans, Bloys Peter

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dc.contributor.advisor	Modro, Tom A	en_ZA
dc.contributor.author	Rijkmans, Bloys Peter	en_ZA
dc.date.accessioned	2015-07-14T09:02:35Z
dc.date.available	2015-07-14T09:02:35Z
dc.date.issued	1981	en_ZA
dc.identifier.citation	Rijkmans, B. 1981. Dimethyl N-Aryl phosphoramidates : structural effects on bonding and solvolytic reactivity. University of Cape Town.	en_ZA
dc.identifier.uri	http://hdl.handle.net/11427/13518
dc.description	Bibliography: p. 84-86.	en_ZA
dc.description.abstract	The acid catalysed hydrolysis of a number of ring alkyl substituted dimethyl N-aryl phosphoramidates, (MeO)2P(0)NHAr, has been studied by measuring the rates of hyd~olysis with the aid of a UV spectrophotometer. These rates have been correlated with the pKa values of the corresponding ani I inium iOhs and the slope of this reactivitybasicity relationship for phosphoramidate with ortho substituents (6 = 0~85) is found to differ from that for substrates with meta and para substituents (S = 0,36). Determination of the thermodynamic parameters indicates that the entropy of activation is approximately constant for the substrates studied and the strongly negative values ~ -I -I (~S = 155,4 - 17,5 J mole K ) are consistent with an A2 type mechanism.	en_ZA
dc.language.iso	eng	en_ZA
dc.subject.other	Organic Chemistry	en_ZA
dc.title	Dimethyl N-Aryl phosphoramidates : structural effects on bonding and solvolytic reactivity	en_ZA
dc.type	Master Thesis
uct.type.publication	Research	en_ZA
uct.type.resource	Thesis	en_ZA
dc.publisher.institution	University of Cape Town
dc.publisher.faculty	Faculty of Science	en_ZA
dc.publisher.department	Department of Chemistry	en_ZA
dc.type.qualificationlevel	Masters
dc.type.qualificationname	MSc	en_ZA
uct.type.filetype	Text
uct.type.filetype	Image
dc.identifier.apacitation	Rijkmans, B. P. (1981). <i>Dimethyl N-Aryl phosphoramidates : structural effects on bonding and solvolytic reactivity</i>. (Thesis). University of Cape Town ,Faculty of Science ,Department of Chemistry. Retrieved from http://hdl.handle.net/11427/13518	en_ZA
dc.identifier.chicagocitation	Rijkmans, Bloys Peter. <i>"Dimethyl N-Aryl phosphoramidates : structural effects on bonding and solvolytic reactivity."</i> Thesis., University of Cape Town ,Faculty of Science ,Department of Chemistry, 1981. http://hdl.handle.net/11427/13518	en_ZA
dc.identifier.vancouvercitation	Rijkmans BP. Dimethyl N-Aryl phosphoramidates : structural effects on bonding and solvolytic reactivity. [Thesis]. University of Cape Town ,Faculty of Science ,Department of Chemistry, 1981 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/13518	en_ZA
dc.identifier.ris	TY - Thesis / Dissertation AU - Rijkmans, Bloys Peter AB - The acid catalysed hydrolysis of a number of ring alkyl substituted dimethyl N-aryl phosphoramidates, (MeO)2P(0)NHAr, has been studied by measuring the rates of hyd~olysis with the aid of a UV spectrophotometer. These rates have been correlated with the pKa values of the corresponding ani I inium iOhs and the slope of this reactivitybasicity relationship for phosphoramidate with ortho substituents (6 = 0~85) is found to differ from that for substrates with meta and para substituents (S = 0,36). Determination of the thermodynamic parameters indicates that the entropy of activation is approximately constant for the substrates studied and the strongly negative values ~ -I -I (~S = 155,4 - 17,5 J mole K ) are consistent with an A2 type mechanism. DA - 1981 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1981 T1 - Dimethyl N-Aryl phosphoramidates : structural effects on bonding and solvolytic reactivity TI - Dimethyl N-Aryl phosphoramidates : structural effects on bonding and solvolytic reactivity UR - http://hdl.handle.net/11427/13518 ER -	en_ZA