Investigations of mycobacteria-specific memoryy/effector T cell responses in HIV infected children receiving antiretroviral therapy

 

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dc.contributor.advisor Hanekom, Willem en_ZA
dc.contributor.advisor Scriba, Thomas en_ZA
dc.contributor.advisor Kampmann, Beate en_ZA
dc.contributor.author Tena-Coki, Nontobeko Gwendoline en_ZA
dc.date.accessioned 2015-01-07T13:32:05Z
dc.date.available 2015-01-07T13:32:05Z
dc.date.issued 2011 en_ZA
dc.identifier.citation Tena-Coki, N. 2011. Investigations of mycobacteria-specific memoryy/effector T cell responses in HIV infected children receiving antiretroviral therapy. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/11689
dc.description Includes abstract. en_ZA
dc.description Includes bibliographical references (leaves 170-210). en_ZA
dc.description.abstract Human immunodeficiency virus (HIV) infected children are at greater risk of developing tuberculosis disease, and might benefit from vaccination with novel TB vaccines. However, little is known about the effect of HIV-infection on function and phenotype of T cell responses to mycobacterial antigens in children. This study compares both CD4 and CD8 T cell cytokine expression and memory phenotype in children, following in vitro stimulation with mycobacterial antigens, also contained in novel anti-TB vaccines that are currently undergoing clinical trials. en_ZA
dc.language.iso eng en_ZA
dc.subject.other Infectious Disease and Molecular Medicine en_ZA
dc.title Investigations of mycobacteria-specific memoryy/effector T cell responses in HIV infected children receiving antiretroviral therapy en_ZA
dc.type Thesis / Dissertation en_ZA
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Institute of Infectious Disease and Molecular Medicine en_ZA
dc.type.qualificationlevel Doctoral en_ZA
dc.type.qualificationname PhD en_ZA
uct.type.filetype Text
uct.type.filetype Image


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