Cellular immunity of naïve and BCG vaccinated neonates

 

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dc.contributor.advisor Kaplan, Gilla en_ZA
dc.contributor.author Watkins, Marcia Linda Vivienne en_ZA
dc.date.accessioned 2015-01-02T09:16:34Z
dc.date.available 2015-01-02T09:16:34Z
dc.date.issued 2010 en_ZA
dc.identifier.citation Watkins, M. 2010. Cellular immunity of naïve and BCG vaccinated neonates. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/10984
dc.description Includes abstract. en_ZA
dc.description Includes bibliographical references (leaves 153-187). en_ZA
dc.description.abstract Despite more than 95% vaccination coverage with Mycobacterium bovis Bacille Calmette-Guérin (BCG), tuberculosis (TB) remains epidemic in South Africa. The dichotomy that successful pregnancy is usually associated with a type 2 (Th2) cytokine profile in the newborn child, whereas immunity to Mycobacterium tuberculosis (Mtb) is associated with the development of a type 1 helper (Th1) cytokine response, could impact on the subsequent adaptive immune response to BCG vaccination. Previous studies have suggested that immune responses in early life may be defective and related to the immaturity of antigen-presenting cells and/or T cells. en_ZA
dc.language.iso eng en_ZA
dc.subject.other Medicine en_ZA
dc.title Cellular immunity of naïve and BCG vaccinated neonates en_ZA
dc.type Doctoral Thesis
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Health Sciences en_ZA
dc.publisher.department Department of Medicine en_ZA
dc.type.qualificationlevel Doctoral
dc.type.qualificationname PhD en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Watkins, M. L. V. (2010). <i>Cellular immunity of naïve and BCG vaccinated neonates</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/10984 en_ZA
dc.identifier.chicagocitation Watkins, Marcia Linda Vivienne. <i>"Cellular immunity of naïve and BCG vaccinated neonates."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2010. http://hdl.handle.net/11427/10984 en_ZA
dc.identifier.vancouvercitation Watkins MLV. Cellular immunity of naïve and BCG vaccinated neonates. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2010 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/10984 en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Watkins, Marcia Linda Vivienne AB - Despite more than 95% vaccination coverage with Mycobacterium bovis Bacille Calmette-Guérin (BCG), tuberculosis (TB) remains epidemic in South Africa. The dichotomy that successful pregnancy is usually associated with a type 2 (Th2) cytokine profile in the newborn child, whereas immunity to Mycobacterium tuberculosis (Mtb) is associated with the development of a type 1 helper (Th1) cytokine response, could impact on the subsequent adaptive immune response to BCG vaccination. Previous studies have suggested that immune responses in early life may be defective and related to the immaturity of antigen-presenting cells and/or T cells. DA - 2010 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2010 T1 - Cellular immunity of naïve and BCG vaccinated neonates TI - Cellular immunity of naïve and BCG vaccinated neonates UR - http://hdl.handle.net/11427/10984 ER - en_ZA


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