Synthesis and characterisation of palladium, platinum and gold complexes and their biological activity against oesophageal cancer cell lines

Doctoral Thesis

2010

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University of Cape Town

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Abstract
New iminophosphine ligands were synthesised in good yields from the condensation of N-(2-(diphenylphosphino)benzaldehyde with the appropriate amine. A series of new metal complexes (Pd, Pt and Au) were obtained by coordination of the iminophosphine ligands in good yields. The complexes were characterised using the spectroscopic and analytical techniques mentioned above, with the exception of the palladium dichloride complexes that are highly insoluble in organic solvents.
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