P450 biochips : development of a protein microarray platform for investigating cytochrome P450 clinical drug metabolism

Doctoral Thesis

2010

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University of Cape Town

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This thesis describes the development of a novel cytochrome P450 array format, the P450 Biochip that allows quantitative and truly high-throughput measurement of cytochrome P450-mediated turnover reactions in sub-nanolitre volumes.
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Includes bibliographical references (leaves 224-243).

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