Author:Munung, Nchangwi SyntiaDate:2016Introduction: Genomics research raises a number of ethical, legal and social issues (ELSI), one of which is the concept of benefit sharing. While benefits and benefit sharing are difficult to discuss because of questions on what needs to be ...Read more
Author:Heathfield, Laura J; Maistry, Sairita; Martin, Lorna J; Ramesar, Raj; de Vries, JantinaDate:29 Nov 2017Background: The use of tissue collected at a forensic post-mortem for forensic genetics research purposes remains of ethical concern as the process involves obtaining informed consent from grieving family members. Two forensic genetics research ...Read more
Author:Masiye, Francis; Mayosi, Bongani; de Vries, JantinaDate:15 Feb 2017Background: Advances in genetic and genomic research have introduced challenges in obtaining informed consent for research in low and middle-income settings. However, there are only few studies that have explored challenges in obtaining ...Read more
Author:van Schalkwyk, Gerrit; de Vries, Jantina; Moodley, KeymanthriDate:2012BACKGROUND: The banking of biological samples raises a number of ethical issues in relation to the storage, export and re-use of samples. Whilst there is a growing body of literature exploring participant perspectives in North America and ...Read morecb
Author:Van Niekerk, KatrynDate:2015Sickle Cell Disease (SCD) is an autosomal recessively inherited blood disorder that leads to a debilitating systemic illness. Although the disease was initially found predominantly in tropical and subtropical regions, SCD has now become a ...Read more
Author:Karen, Kengne KamgaDate: 2021Introduction: Fragile X Syndrome (FXS) is the most common genetic cause of intellectual disability (ID) and Autism Spectrum Disorder (ASD). It is caused by the expansion of CGG (Cytosine, Guanine, Guanine) repeats at the 5' untranslated region ...Read more
Author:Faure, Marlyn CollinDate:2018There is mixed evidence about how genetic attribution of disease may impact on stigma. One theory, based on essentialism, argues that knowledge of genetic attribution may increase stigma, while attribution theory argues that bio-genetic ...Read more