Author:Habte, Habtom; de Beer, Corena; Lotz, Zoe; Roux, Paul; Mall, AnwarDate:2010BACKGROUND: We have previously shown that MUC5B and MUC7 mucins from saliva of HIV negative individuals inhibit HIV-1 activity by 100% in an in vitro assay. The purpose of this subsequent study was to investigate whether MUC5B and MUC7 from ...Read morecb
Author:Mall, Anwar S; Habte, Habtom; Mthembu, Yolanda; Peacocke, Julia; de Beer, CorenaDate:06 Oct 2017Background: Mucins are large O-linked glycosylated proteins which give mucus their gel-forming properties. There are indications that mucus and mucins in saliva, breast milk and in the cervical plug inhibit the human immunodeficiency virus ...Read morecb
Author:Habte, Habtom H; Mall, Anwar S; de Beer, Corena; Lotz E, Zoe; Kahn, DelawirDate:2006BACKGROUND: Despite the continuous shedding of HIV infected blood into the oral cavity and the detectable presence of the AIDS virus at a high frequency, human saliva is reported to inhibit oral transmission of HIV through kissing, dental ...Read morecb
Author:Peacocke, Julia; Lotz, Zoe; de Beer, Corena; Roux, Paul; Mall, AnwarDate:2012BACKGROUND:Sub-Saharan Africa is the world's worst HIV-AIDS affected region. More interventions to manage this pandemic are urgently required. Transmission of the virus through an exchange of saliva is rarely known to occur. This project ...Read morecb