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Browsing by Author "Warren, Robin M"

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A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic

Author: Klopper, Marisa ; Heupink, Tim H ; Hill-Cawthorne, Grant ; Streicher, Elizabeth M ; Dippenaar, Anzaan ; de Vos, Margaretha ; Abdallah, Abdallah M ; Limberis, Jason ; Merker, Matthias ; Burns, Scott ; Niemann, Stefan ; Dheda, Keertan ; Posey, James ; Pain, Arnab ; Warren, Robin M Date: 21 Feb 2020 Abstract Background Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and ... Read more
A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic

Author: Klopper, Marisa ; Heupink, Tim H ; Hill-Cawthorne, Grant ; Streicher, Elizabeth M ; Dippenaar, Anzaan ; de Vos, Margaretha ; Abdallah, Abdallah M ; Limberis, Jason ; Merker, Matthias ; Burns, Scott ; Niemann, Stefan ; Dheda, Keertan ; Posey, James ; Pain, Arnab ; Warren, Robin M Date: 04 Feb 2020 Abstract Background Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is ... Read more
Identifying nucleic acid-associated proteins in Mycobacterium smegmatis by mass spectrometry-based proteomics

Author: Kriel, Nastassja L ; Heunis, Tiaan ; Sampson, Samantha L ; Gey van Pittius, Nico C ; Williams, Monique J ; Warren, Robin M Date: 23 Mar 2020 Abstract Background Transcriptional responses required to maintain cellular homeostasis or to adapt to environmental stress, is in part mediated by several nucleic-acid associated proteins. ... Read more
A treatment recommender clinical decision support system for personalized medicine: method development and proof-of-concept for drug resistant tuberculosis

Author: Verboven, Lennert ; Calders, Toon ; Callens, Steven ; Black, John ; Maartens, Gary ; Dooley, Kelly E ; Potgieter, Samantha ; Warren, Robin M ; Laukens, Kris ; Van Rie, Annelies Date: 02 Mar 2022 Background Personalized medicine tailors care based on the patient’s or pathogen’s genotypic and phenotypic characteristics. An automated Clinical Decision Support System (CDSS) could help translate the genotypic and phenotypic ... Read more c b

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Browsing by Author "Warren, Robin M"

Browsing by Author "Warren, Robin M"

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