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Browsing by Author "Stein, Dan"

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A functional magnetic resonance imaging study of cognitive emotion regulation in relation to individual differences in self-esteem

Author: Swan, Freda Zoë Date: 2020 Objectives Self-esteem may affect the processing and regulation of emotion. However, it is unclear whether differences in self-esteem are associated with changes in initial emotional appraisal or engagement of emotion regulation. I investigated ... Read more
An investigation of a neuro-inflammatory profile of HIV-associated neurocognitive disorders

Author: Williams, Monray Edward Date: 2021 Background HIV-associated neurocognitive disorder (HAND) is the consequence of the effects of HIV-1 within the central nervous system (CNS). HIV-associated neurocognitive impairment differs in severity with milder forms presenting in 50% of ... Read more
Childhood trauma in adults with social anxiety disorder and panic disorder: a cross-national study

Author: Lochner, C ; Seedat, S ; Allgulander, C ; Kidd, M ; Stein, Dan ; Gerdner, A Date: 2010 Objectives: The influence of childhood trauma as a specific environmental factor on the development of adult psychopathology is far from being elucidated. As part of a collaborative project between research groups from South Africa (SA) and ... Read more
Comparing the accuracy of brief versus long depression screening instruments which have been validated in low and middle income countries: a systematic review

Author: Akena, Dickens ; Joska, John ; Obuku, Ekwaro ; Amos, Taryn ; Musisi, Seggane ; Stein, Dan Date: 2012 BACKGROUND: Given the high prevalence of depression in primary health care (PHC), the use of screening instruments has been recommended. Both brief and long depression screening instruments have been validated in low and middle income countries ... Read more c b
DSM-5: a collection of psychiatrist views on the changes, controversies, and future directions

Author: Nemeroff, Charles ; Weinberger, Daniel ; Rutter, Michael ; MacMillan, Harriet ; Bryant, Richard ; Wessely, Simon ; Stein, Dan ; Pariante, Carmine ; Seemuller, Florian ; Berk, Michael ; Malhi, Gin ; Preisig, Martin ; Brune, Martin ; Lysaker, Paul Date: 2013 The recent release of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) by the American Psychiatric Association has led to much debate. For this forum article, we asked BMC Medicine Editorial Board members ... Read more c b
The effectiveness of problem solving therapy in deprived South African communities: results from a pilot study

Author: van't Hof, Edith ; Stein, Dan ; Marks, Isaac ; Tomlinson, Mark ; Cuijpers, Pim Date: 2011 BACKGROUND:The majority of South Africans with a DSM-IV diagnosis receive no treatment for their mental health problems. There is a move to simplify treatment for common mental disorders (CMDs) in order to ease access. Brief problem solving ... Read more c b
Evidence-based treatment for Depersonalisation-derealisation Disorder (DPRD)

Author: Somer, Eli ; Amos-Williams, Taryn ; Stein, Dan Date: 2013 BACKGROUND: Depersonalisation-derealisation disorder (DPRD) is a distressing and impairing condition with a pathophysiology that is not well understood. Nevertheless, given the growing interest in its pathogenesis, and the publication of a ... Read more c b
Explanatory models of mental disorders and treatment practices among traditional healers in Mpumalanga South Africa

Author: Sorsdahl, Katherine Rae ; Flisher, Alan ; Wilson, Z ; Stein, Dan Date: 2010 Objective: In many traditional belief systems in Africa, including South Africa, mental health problems may be attributed to the influence of ancestors or to bewitchment. Traditional healers are viewed as having the expertise to address these ... Read more
Final Year Medical Students' Experience of Bullying: A Study at the University of Cape Town

Author: Fakroodeen, Adam Abdul Kader Date: 2020 Background: Medical bullying has been identified as a growing concern internationally, with multiple studies showing a high prevalence in medical students and residents However, several questions remain unanswered, including a) the prevalence ... Read more
Global mental health and neuroethics

Author: Stein, Dan ; Giordano, James Date: 2015 BACKGROUND: Global mental health is a relatively new field that has focused on disparities in mental health services across different settings, and on innovative ways to provide feasible, acceptable, and effective services in poorly-resourced ... Read more c b
Impact of childhood trauma on functionality and quality of life in HIV-infected women

Author: Troeman, Zyrhea ; Spies, Georgina ; Cherner, Mariana ; Archibald, Sarah ; Fennema-Notestine, Christine ; Theilmann, Rebecca ; Spottiswoode, Bruce ; Stein, Dan ; Seedat, Soraya Date: 2011 BACKGROUND:While there are many published studies on HIV and functional limitations, there are few in the context of early abuse and its impact on functionality and Quality of Life (QoL) in HIV. METHODS: The present study focused on HIV in ... Read more c b
Investigating neuroinflammation in schizophrenia: a proton magnetic resonance spectroscopy (1H-MRS) and cytokine study

Author: Burger, Antoinette Date: 2022 Introduction: There are similarities in the phenomenology and psychobiology of schizophrenia and methamphetamine psychosis, with evidence of alterations in glutamatergic function in both conditions, and of involvement of inflammatory pathways ... Read more
Investigation of the Shared Genetic Influences on Bipolar Disorder, Borderline Personality Disorder and Regional Brain Structures

Author: Campbell, Megan Date: 2021 Background: The heritabilities of bipolar disorder (BD) and borderline personality disorder (BPD) are 80% and 65%, respectively, indicating substantial genetic contributions to both disorders. BD and BPD are often comorbid, and both disorders ... Read more
MIMS Handbook of Psychiatric Medication

Author: Stein, Dan ; Hoffman, Jacob ; Kadenge, Betty Date: 2022 There is general agreement on the value of evidence-based medicine in general practice. And there is growing acknowledgement that the treatment of psychiatric disorders is an important component of primary care. This volume addresses the ... Read more
Mindfulness based cognitive therapy improves frontal control in bipolar disorder: a pilot EEG study

Author: Howells, Fleur ; Ives-Deliperi, Victoria ; Horn, Neil ; Stein, Dan Date: 2012 BACKGROUND: Cognitive processing in Bipolar Disorder is characterized by a number of attentional abnormalities. Mindfulness Based Cognitive Therapy combines mindfulness meditation, a form of attentional training, along with aspects of cognitive ... Read more c b
Negative attributions towards people with substance use disorders in South Africa: Variation across substances and by gender

Author: Sorsdahl, Katherine ; Stein, Dan ; Myers, Bronwyn Date: 2012 BACKGROUND:Little research has examined attitudes towards people who use substances in low and middle income countries (LMIC). Therefore, the present study examined the attributions made by the general South African population about people ... Read more c b
Neurocircuitry of attention in methamphetamine induced psychosis: a comparison against schizophrenia patients and healthy controls

Author: Hsieh, Jennifer Hsin-Wen Date: 2022 Background Methamphetamine induced psychosis (MAP) and schizophrenia present with similar positive symptoms of psychosis, are characterized by evidence of attentional impairment, and show symptomatic response to treatment with dopamine ... Read more
Neuroimaging and neurocognitive assessment of PTSD and MDD in a South African community setting

Author: Koopowitz, Sheri Date: 2019 Background: There is growing evidence of abnormalities in neurocognition, neuroanatomy, and functional connectivity in posttraumatic stress disorder (PTSD) and major depressive disorder (MDD). However, there has been less work on individuals ... Read more
Neuropsychological assessment for first-episode psychosis patients in low resource settings

Author: Mwesiga, Emmanuel Kiiza Date: 2021 Introduction: Cognitive impairment is the most significant predictor of long-term outcomes in psychotic disorders, and neuropsychological assessment is therefore recommended in first-episode psychosis patients. However, the literature on ... Read more
Neuropsychological outcomes in adults commencing highly active anti-retroviral treatment in South Africa: a prospective study

Author: Joska, John ; Westgarth-Taylor, Jennifer ; Hoare, Jacqueline ; Thomas, Kevin ; Paul, Robert ; Myer, Landon ; Stein, Dan Date: 2012 BACKGROUND:Infection with HIV may result in significant neuropsychological impairment, especially in late stage disease. To date, there have been no cohort studies of the impact of highly active anti-retroviral treatment (HAART) in South ... Read more c b

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