Author:Malande, Oliver OmbevaDate:2019Introduction: Bloodstream infection (BSI) is an important cause of morbidity and mortality in children (1). There are few descriptions of Escherichia coli (E. coli) BSI in children, particularly in Africa, yet E. coli is increasing in importance ...Read more
Author:Davies, Mary-Ann; Boulle, Andrew; Fakir, Tanzeem; Nuttall, James; Eley, BrianDate:2008BACKGROUND:Antiretroviral therapy (ART) dramatically improves outcomes for children in Africa; however excellent adherence is required for treatment success. This study describes the utility of different measures of adherence in detecting ...Read morecb
Author:Lochan, Harsha; Pillay, Vashini; Bamford, Colleen; Nuttall, James; Eley, BrianDate:06 Dec 2017Background: Bloodstream infection (BSI) in children causes significant morbidity and mortality. There are few studies describing the epidemiology of BSI in South African children. Methods: A retrospective descriptive cohort study was conducted ...Read more
Author:Gebremicael, Mulugeta NaizgiDate: 2022Introduction Candida bloodstream infection (BSI) causes appreciable mortality in children. There are few studies describing the epidemiology of Candida BSI in children living in the Western Cape province of South Africa. Methods A retrospective ...Read more
Author:Ogunbosi, Babatunde OluwatosinDate:2020Introduction: There are few studies describing colonisation with extended spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) and carbapenem-resistant Enterobacterales (CRE) among children in subSaharan Africa. Colonisation often ...Read more
Author:Naidoo, Reené; Nuttall, James; Whitelaw, Andrew; Eley, BrianDate:2013BACKGROUND: Staphylococcus aureus is an important pathogen in paediatric patients with bloodstream infections. The epidemiology of S. aureus bacteraemia, however, has not been well documented in children in South Africa. METHODS: A retrospective ...Read morecb
Author:Nuttall, James; Eley, Brian; Honikman, SimoneDate:2004The prevention of mother-to-child transmission (PMTCT) programme in the Western Cape is said to have achieved 100% coverage.1 This implies that all pregnant women who attend an antenatal health care facility in the public sector are offered ...Read more
Author:van Zyl, Gert; Rabie, Helena; Nuttall, James; Cotton, MarkDate:2011BACKGROUND: The historic use of full-dose ritonavir as part of an unboosted protease inhibitor (PI)-based antiretroviral therapy regimen in some South African children contributes to the frequent accumulation of major PI resistance mutations. ...Read morecb
Author:Dame, Joycelyn A; Beylis, Natalie; Nuttall, James; Eley, BrianDate:07 Oct 2020Background
This study describes the disease burden, clinical characteristics, antibiotic management, impact of multidrug resistance and outcome of Pseudomonas aeruginosa bloodstream infection (PABSI) among children admitted to a tertiary ...Read more
Author:Dame, Joycelyn AssimengDate: 2020Introduction This study describes the disease burden, clinical characteristics, antibiotic management, impact of multidrug resistance and outcome of Pseudomonas aeruginosa bloodstream infection (PABSI) among children admitted to a tertiary ...Read more
Author:Enimil, Anthony KwameDate: 2021Introduction World Health Organization approved the use of Xpert MTB/RIF Ultra (Ultra) in children due to quick turn-around time, improved yield over smear microscopy, and ability to detect rifampicin resistance despite culture being the “gold ...Read more