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Browsing by Author "Mabuza, Aaron"

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Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use in Mpumalanga Province, South Africa (2001–2018)

Author: Raman, Jaishree ; Kagoro, Frank M ; Mabuza, Aaron ; Malatje, Gillian ; Reid, Anthony ; Frean, John ; Barnes, Karen I Date: 22 Aug 2019 Abstract Background The ability of Plasmodium falciparum parasites to develop resistance to widely used anti-malarials threatens malaria control and elimination efforts. Regular drug efficacy ... Read more
Exploring the seasonality of reported treated malaria cases in Mpumalanga, South Africa

Author: Silal, Sheetal Prakash ; Barnes, Karen I ; Kok, Gerdalize ; Mabuza, Aaron ; Little, Francesca Date: 2013 South Africa, having met the World Health Organisation's pre-elimination criteria, has set a goal to achieve malaria elimination by 2018. Mpumalanga, one of three provinces where malaria transmission still occurs, has a malaria season subject ... Read more c b
Safety and tolerability of single low-dose primaquine in a low-intensity transmission area in South Africa: an open-label, randomized controlled trial

Author: Raman, Jaishree ; Allen, Elizabeth ; Workman, Lesley ; Mabuza, Aaron ; Swanepoel, Hendrik ; Malatje, Gillian ; Frean, John ; Wiesner, Lubbe ; Barnes, Karen I Date: 24 Jun 2019 Abstract Background To reduce onward falciparum malaria transmission, the World Health Organization recommends adding single low-dose (SLD) primaquine to artemisinin-based combination treatment ... Read more
Therapeutic efficacy of sulfadoxine-pyrimethamine for plasmodium falciparum malaria

Author: Mabuza, Aaron ; Govere, John ; La Grange, Kobus ; Mngomezulu, Nicros ; Allen, Elizabeth ; Zitha, Alpheus ; Mbokazi, Frans ; Durrheim, David ; Barnes, Karen Date: 2005 Objectives. To assess the therapeutic efficacy of sulfadoxinepyrimethamine (SP) after 5 years of use as first-line treatment of uncomplicated Plasmodium falciparum malaria, and thus guide the selection of artemisinin-based combination therapy ... Read more

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Browsing by Author "Mabuza, Aaron"

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