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Browsing by Author "Hussey, Gregory D"

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A systematic review of the epidemiology of hepatitis A in Africa

Author: Patterson, Jenna ; Abdullahi, Leila ; Hussey, Gregory D ; Muloiwa, Rudzani ; Kagina, Benjamin M Date: 22 Jul 2019 Abstract Background Hepatitis A, caused by the hepatitis A virus (HAV), is a vaccine preventable disease. In Low and Middle-Income Countries (LMICs), poor hygiene and sanitation conditions are ... Read more
A bibliometric analysis of childhood immunization research productivity in Africa since the onset of the Expanded Program on Immunization in 1974

Author: Wiysonge, Charles S ; Uthman, Olalekan A ; Ndumbe, Peter M ; Hussey, Gregory D Date: 14 Mar 2013 Background: The implementation of strategic immunization plans whose development is informed by available locally-relevant research evidence should improve immunization coverage and prevent disease, disability and death in Africa. In general, ... Read more c b
Building evidence for improving childhood immunisation coverage in Africa.

Author: Wiysonge, Shey Umaru Charles Date: 2012 The Expanded Programme on Immunisation has the potential to substantially reduce child mortality and contribute to achieving the Millennium Development Goals. We assessed the programme’s performance in Africa, the reasons for poor performance, ... Read more
A descriptive study of the attitudes of doctors, working at clinics and day hospitals in the Cape Metropole to patients with HIV/AIDS

Author: Fransman, Desireé Christine Date: 1998 HIV/AIDS is a fairly new condition. Despite a large amount of published literature regarding its clinical aspects, there is a paucity of South African research and information relating to the attitudes and feelings of the physicians who ... Read more
Determinants of vaccine hesitancy in Africa: a systematic review

Author: Paone, Alexander Date: 2017 This MPH dissertation is a systematic review of the factors contributing to vaccine hesitancy in Africa. The dissertation comprises of the following three parts: The research protocol (Part A) outlines the background and proposed methods of ... Read more
Epidemiology of pertussis in children hospitalised with respiratory tract infection

Author: Muloiwa, Rudzani Date: 2021 The availability of an effective vaccine against Bordetella pertussis substantially reduced the morbidity and mortality from pertussis, however, in the last decade there appears to have been a substantial increase in pertussis cases as reported ... Read more
Hepatitis A seroprevalence in South Africa: Are we in epidemiological transition?

Author: Enoch, Annabel Date: 2018 Hepatitis A virus (HAV) is the most common cause of viral hepatitis worldwide. Infection with HAV is vaccine preventable, however, a vaccine against HAV is not included in the Expanded Programme on Immunization in South Africa (SA). South ... Read more
Individual and contextual factors associated with low childhood immunisation coverage in sub-Saharan Africa: a multilevel analysis

Author: Wiysonge, Charles S ; Uthman, Olalekan A ; Ndumbe, Peter M ; Hussey, Gregory D Date: 2012 BACKGROUND: In 2010, more than six million children in sub-Saharan Africa did not receive the full series of three doses of the diphtheria-tetanus-pertussis vaccine by one year of age. An evidence-based approach to addressing this burden of ... Read more c b
Knowledge, attitudes and practices on adolescent vaccination among parents, teachers and adolescents in Africa: a systematic review protocol

Author: Abdullahi, Leila H ; Kagina, Benjamin M ; Cassidy, Tali ; Adebayo, Esther F ; Wiysonge, Charles S ; Hussey, Gregory D Date: 09 Sep 2014 Background: Vaccines are the most successful and cost-effective public health interventions available to avert vaccine-preventable diseases and deaths. Despite progress in the field of adolescent health, many young people in Africa still get ... Read more c b
Mobile phone text messaging for promoting adherence to anti-tuberculosis treatment: a systematic review protocol

Author: Nglazi, Mweete ; Bekker, Linda-Gail ; Wood, Robin ; Hussey, Gregory D ; Wiysonge, Charles S Date: 2013 BACKGROUND: In 2010, there were approximately 8.8 million incident cases of tuberculosis (TB) worldwide. The treatment of TB is at least six months long and may be complicated by a high pill burden. In addition, TB patients often do not take ... Read more c b
Passive smoking and meningococcal disease

Author: Moodley, Jennifer R Date: 1997 Neiserria meningitidis remains an important cause of morbidity and mortality in South Africa (SA). It is the sixth commonest cause of notified disease with a case fatality rate of 11% for the period 1990 1994. Identification of preventable ... Read more
A retrospective study assessing the clinical outcomes and costs of acute hepatitis A in Cape Town, South Africa

Author: Patterson, Jenna ; Cleary, Susan ; Silal, Sheetal P ; Hussey, Gregory D ; Enoch, Annabel ; Korsman, Stephen ; Goddard, Elizabeth ; Setshedi, Mashiko ; Spearman, Wendy C ; Kagina, Benjamin M ; Muloiwa, Rudzani Date: 11 Jan 2022 Background While some evidence has been demonstrated the cost-effectiveness of routine hepatitis A vaccination in middle-income countries, the evidence is still limited in other settings including in South Africa. Given this, ... Read more c b
Rifampin pharmacokinetics in children, with and without human immunodeficiency virus infection, hospitalized for the management of severe forms of tuberculosis

Author: Schaaf, Hendrik S ; Willemse, Marianne ; Cilliers, Karien ; Labadarios, Demetre ; Maritz, Johannes S ; Hussey, Gregory D ; McIlleron, Helen ; Smith, Peter ; Donald, Peter R Date: 2009 BACKGROUND: Rifampin is a key drug in antituberculosis chemotherapy because it rapidly kills the majority of bacilli in tuberculosis lesions, prevents relapse and thus enables 6-month short-course chemotherapy. Little is known about the ... Read more c b
School based versus supplemental vaccination strategies in the delivery of vaccines to 5-19 year olds in Africa - a systematic review

Author: Haddison, Christiana Eposi Date: 2017 Background: Some vaccine preventable diseases still remain a public health burden in many African countries. The occurrence of vaccine preventable diseases in all age groups has led to the realization of the need to extend routine immunisation ... Read more
A situation analysis of street children in Harare, Zimbabwe

Author: Pascoe, Margaret Joy Date: 1996 The problem of children on the streets of Harare has been increasing over the last five years. The majority of these children appear to be of school-going age. Who are these children? Where do they live? Why are they not attending school? ... Read more
Strengthening the expanded programme on immunization in Africa: looking beyond 2015

Author: Machingaidze, Shingai ; Wiysonge, Charles S ; Hussey, Gregory D Date: 2013 Shingai Machingaidze and colleagues reflect on the successes and shortfalls of the Expanded Programme on Immunization (EPI) in Africa, and the considerable challenges that must now be addressed to improve immunization systems. Read more c b
The burden of laboratory-confirmed pertussis in low- and middle-income countries since the inception of the Expanded Programme on Immunisation (EPI) in 1974: a systematic review and meta-analysis

Author: Muloiwa, Rudzani ; Kagina, Benjamin M ; Engel, Mark E ; Hussey, Gregory D Date: 28 Aug 2020 Abstract Background An effective vaccine against Bordetella pertussis was introduced into the Expanded Programme on Immunisation (EPI) by WHO in 1974, leading to a substantial global reduction in pertussis morbidity and mortality. In low- ... Read more
The tuberculin skin test versus QuantiFERON TB Gold® in predicting tuberculosis disease in an adolescent cohort study in South Africa

Author: Mahomed, Hassan ; Hawkridge, Tony ; Verver, Suzanne ; Abrahams, Deborah ; Geiter, Lawrence ; Hatherill, Mark ; Ehrlich, Rodney ; Hanekom, Willem A ; Hussey, Gregory D Date: 2011 Setting This study was conducted in a high tuberculosis (TB) burden area in Worcester, South Africa, with a notified all TB incidence rate of 1,400/100,000. Main Objective To compare the predictive value of a baseline tuberculin skin test ... Read more c b
Vitamin A status of HIV-infected adults in South Africa

Author: Visser, Marianne Emilie Date: 1998 Introduction: Several studies in developed countries such as the USA have reported low serum or plasma vitamin A levels in adults with HIV disease. Limited data suggests that HIV-infected adults from developing countries show even lower vitamin ... Read more