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Browsing by Author "Gumedze, Freedom"

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Clinical characteristics and initial management of patients with tuberculous pericarditis in the HIV era: the Investigation of the Management of Pericarditis in Africa (IMPI Africa) registry

Author: Mayosi, Bongani ; Wiysonge, Charles ; Ntsekhe, Mpiko ; Volmink, Jimmy ; Gumedze, Freedom ; Maartens, Gary ; Aje, Akinyemi ; Thomas, Baby ; Thomas, Kandathil ; Awotedu, Abolade ; Thembela, Bongani ; Mntla, Phindile ; Maritz, Frans ; Blackett, Kathleen ; Nkouonlack, Date: 2006 BACKGROUND:The incidence of tuberculous pericarditis has increased in Africa as a result of the human immunodeficiency virus (HIV) epidemic. However, the effect of HIV co-infection on clinical features and prognosis in tuberculous pericarditis ... Read more c b
Detection and down-weighting of outliers in non-normal data: theory and application

Author: Chatora,Tinashe Daniel Date: 15 Aug 2014 Read more
Diagnostics for joint models for longitudinal and survival data

Author: Singini, Isaac Luwinga Date: 2021 Joint models for longitudinal and survival data are a class of models that jointly analyse an outcome repeatedly observed over time such as a bio-marker and associated event times. These models are useful in two practical applications; firstly ... Read more
HIV infection is associated with a lower incidence of constriction in presumed tuberculous pericarditis: a prospective observational study

Author: Ntsekhe, Mpiko ; Wiysonge, Charles S ; Gumedze, Freedom ; Maartens, Gary ; Commerford, Patrick J ; Volmink, Jimmy A ; Mayosi, Bongani M Date: 2008 BACKGROUND: Pericardial constriction is a serious complication of tuberculous pericardial effusion that occurs in up to a quarter of patients despite anti-tuberculosis chemotherapy. The impact of human immunodeficiency virus (HIV) infection ... Read more c b
Mortality in patients treated for tuberculous pericarditis in sub-Saharan Africa.

Author: Mayosi, Bongani M ; Wiysonge, Charles Shey ; Ntsekhe, Mpiko ; Gumedze, Freedom ; Volmink Jimmy A ; Maartens, Gary ; Aje, Akinyemi ; Thomas, Baby M ; Thomas, Kandathil M ; Awotedu, Abolade A ; Bongani, Thembela ; Mntla, Phindile ; Maritz, Frans ; Blackett, Kathleen Ngu ; Nkouonlack, Duquesne C ; Burch, Vanessa C ; Rebe, Kevin ; Parrish, Andy ; Sliwa, Karen ; Vezi, Brian Z ; Alam, Nowshad ; Brown, Basil G ; Gould, Trevor ; Visser, Tim ; Magula, Nombulelo P ; Commerford, Patrick J Date: 2008 Tuberculous pericarditis is one of the most severe forms of extrapulmonary tuberculosis, causing death or disability in a substantial proportion of affected people.1,2 In Africa, the incidence of tuberculous pericarditis is rising as a result ... Read more
Pregnancy-associated heart failure: a comparison of clinical presentation and outcome between hypertensive heart failure of pregnancy and idiopathic peripartum cardiomyopathy

Author: Ntusi, Ntobeko B A ; Badri, Motasim ; Gumedze, Freedom ; Sliwa, Karen ; Mayosi, Bongani M Date: 2015 AIMS: There is controversy regarding the inclusion of patients with hypertension among cases of peripartum cardiomyopathy (PPCM), as the practice has contributed significantly to the discrepancy in reported characteristics of PPCM. We sought ... Read more c b
The prevalence, determinants, natural history and impact of atrial fibrillation and atrial flutter in patients with tuberculosis pericarditis - insights from the IMPI trial

Author: Chishala, Chishala Date: 2016 Tuberculosis is the most common cause of pericarditis in Africa. The dual human immunodeficiency virus (HIV)-tuberculosis epidemics are major contributors to the burden of extra-pulmonary tuberculosis, including tuberculous pericarditis. ... Read more
A random effects variance shift model for detecting and accommodating outliers in meta-analysis

Author: Gumedze, Freedom ; Jackson, Dan Date: 2011 BACKGROUND:Meta-analysis typically involves combining the estimates from independent studies in order to estimate a parameter of interest across a population of studies. However, outliers often occur even under the random effects model. The ... Read more c b
Statistical model selection techniques for the cox proportional hazards model: a comparative study

Author: Njati, Jolando Date: 2022 The advancement in data acquiring technology continues to see survival data sets with many covariates. This has posed a new challenge for researchers in identifying important covariates for inference and prediction for a time-to-event response ... Read more
The role and essence of pilot trials and subgroup analysis in cardiovascular research: the IMPI trial experience

Author: Isiguzo, Godsent Chichebem Date: 2019 Background Randomised control trials (RCTs) are capital-intensive projects and demand substantial human and capital resources. Therefore, proper planning, precise research questions and adequate thoughts are required in areas such as ... Read more

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Browsing by Author "Gumedze, Freedom"

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