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Browsing by Author "Gray, Elin S"

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Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection

Author: Moore, Penny L ; Ranchobe, Nthabeleng ; Lambson, Bronwen E ; Gray, Elin S ; Cave, Eleanor ; Abrahams, Melissa-Rose ; Bandawe, Gama ; Mlisana, Koleka ; Karim, Salim S Abdool ; Williamson, Carolyn Date: 2009 Author Summary Most HIV-1 infected individuals develop neutralizing antibodies against their own virus, termed an autologous neutralizing response. It is known that this response exerts pressure on the envelope of HIV, the target of such ... Read more c b
Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes

Author: Wibmer, Constantinos Kurt ; Bhiman, Jinal N ; Gray, Elin S ; Tumba, Nancy ; Karim, Salim S Abdool ; Williamson, Carolyn ; Morris, Lynn ; Moore, Penny L Date: 2013 Identifying the targets of broadly neutralizing antibodies to HIV-1 and understanding how these antibodies develop remain important goals in the quest to rationally develop an HIV-1 vaccine. We previously identified a participant in the CAPRISA ... Read more c b

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