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Browsing by Author "Egger, Matthias"

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Adjusting mortality for loss to follow-up: analysis of five ART programmes in sub-Saharan Africa

Author: Brinkhof, Martin W G ; Spycher, Ben D ; Yiannoutsos, Constantin ; Weigel, Ralf ; Wood, Robin ; Messou, Eugène ; Boulle, Andrew ; Egger, Matthias ; Sterne, Jonathan A C ; (IeDEA), for the International epidemiological Database to Evaluate AIDS Date: 2010 BACKGROUND: Evaluation of antiretroviral treatment (ART) programmes in sub-Saharan Africa is difficult because many patients are lost to follow-up. Outcomes in these patients are generally unknown but studies tracing patients have shown ... Read more c b
Assessing population aging and disability in sub-Saharan Africa: lessons from Malawi?

Author: Stuck, Andreas E ; Tenthani, Lyson ; Egger, Matthias Date: 2013 The study of Payne and colleagues is, to our knowledge, the first empirical study to report disability states, and to estimate transitions between them, for Malawi's population of 45 years of age and older. The study provides detailed estimates ... Read more c b
Correcting mortality for loss to follow-up: a nomogram applied to antiretroviral treatment programmes in sub-Saharan Africa

Author: Egger, Matthias ; Spycher, Ben D ; Sidle, John ; Weigel, Ralf ; Geng, Elvin H ; Fox, Matthew P ; MacPhail, Patrick ; van Cutsem, Gilles ; Messou, Eugène ; Wood, Robin Date: 2011 Background: The World Health Organization estimates that in sub-Saharan Africa about 4 million HIV-infected patients had started antiretroviral therapy (ART) by the end of 2008. Loss of patients to follow-up and care is an important problem ... Read more c b
The cost-effectiveness of monitoring strategies for antiretroviral therapy of HIV infected patients in resource-limited settings: software tool

Author: Estill, Janne ; Salazar-Vizcaya, Luisa ; Blaser, Nello ; Egger, Matthias ; Keiser, Olivia Date: 2015 BACKGROUND: The cost-effectiveness of routine viral load (VL) monitoring of HIV-infected patients on antiretroviral therapy (ART) depends on various factors that differ between settings and across time. Low-cost point-of-care (POC) tests for ... Read more c b
Differences in access and patient outcomes across antiretroviral treatment clinics in the Free State province: A prospective cohorot study

Author: Ingle, Suzanne M ; May, Margaret ; Uebel, Kerry ; Timmerman, Venessa ; Kotze, Eduan ; Bachmann, Max ; Sterne, Jonathan A C ; Egger, Matthias ; Fairall, Lara Date: 2010 Objective. To assess differences in access to antiretroviral treatment (ART) and patient outcomes across public sector treatment facilities in the Free State province, South Africa. Design. Prospective cohort study with retrospective database ... Read more
Effectiveness of Personal Protective Equipment for Healthcare Workers Caring for Patients with Filovirus Disease: A Rapid Review

Author: Hersi, Mona ; Stevens, Adrienne ; Quach, Pauline ; Hamel, Candyce ; Thavorn, Kednapa ; Garritty, Chantelle ; Skidmore, Becky ; Vallenas, Constanza ; Norris, Susan L ; Egger, Matthias Date: 2015 BACKGROUND: A rapid review, guided by a protocol, was conducted to inform development of the World Health Organization’s guideline on personal protective equipment in the context of the ongoing (2013-present) Western African filovirus disease ... Read more c b
Estimating loss to follow-up in HIV-infected patients on antiretroviral therapy: the effect of the competing risk of death in Zambia and Switzerland

Author: Schöni-Affolter, Franziska ; Keiser, Olivia ; Mwango, Albert ; Stringer, Jeffrey ; Ledergerber, Bruno ; Mulenga, Lloyd ; Bucher, Heiner C ; Westfall, Andrew O ; Calmy, Alexandra ; Boulle, Andrew ; Chintu, Namwinga ; Egger, Matthias ; Chi, Benjamin H Date: 2011 BACKGROUND: Loss to follow-up (LTFU) is common in antiretroviral therapy (ART) programmes. Mortality is a competing risk (CR) for LTFU; however, it is often overlooked in cohort analyses. We examined how the CR of death affected LTFU estimates ... Read more c b
Growth and mortality outcomes for different antiretroviral therapy initiation criteria in children ages 1–5 Years: a causal modeling analysis

Author: Schomaker, Michael ; Davies, Mary-Ann ; Malateste, Karen ; Renner, Lorna ; Sawry, Shobna ; N’Gbeche, Sylvie ; Technau, Karl-Günter ; Eboua, François ; Tanser, Frank ; Sygnaté-Sy, Haby ; Phiri, Sam ; Madeleine, Amorissani-Folquet ; Cox, Vivian ; Koueta, Fla ; Chimbete, Cleophas ; Lawson-Evi, Annette ; Giddy, Janet ; Amani-Bosse, Clarisse ; Wood, Robin ; Egger, Matthias ; Leroy, Valeriane Date: 2016 Background: There is limited evidence regarding the optimal timing of initiating antiretroviral therapy (ART) in children. We conducted a causal modeling analysis in children ages 1–5 years from the International Epidemiologic Databases to ... Read more
Hepatitis B infection, viral load and resistance in HIV-infected patients in Mozambique and Zambia

Author: Wandeler, Gilles ; Musukuma, Kalo ; Zürcher, Samuel ; Vinikoor, Michael J ; Llenas-García, Jara ; Aly, Mussa M ; Mulenga, Lloyd ; Chi, Benjamin H ; Ehmer, Jochen ; Hobbins, Michael A ; Bolton-Moore, Carolyn ; Hoffmann, Christopher J ; Egger, Matthias ; IeDEA-Southern Africa Date: 2016 BACKGROUND: Few data on the virological determinants of hepatitis B virus (HBV) infection are available from southern Africa. METHODS: We enrolled consecutive HIV-infected adult patients initiating antiretroviral therapy (ART) at two urban ... Read more c b
HHV-8 seroprevalence: a global view

Author: Rohner, Eliane ; Wyss, Natascha ; Trelle, Sven ; Mbulaiteye, Sam ; Egger, Matthias ; Novak, Urban ; Zwahlen, Marcel ; Bohlius, Julia Date: 2014 BACKGROUND: Human herpes virus 8 (HHV-8) is the underlying infectious cause of Kaposi sarcoma (KS) and other proliferative diseases; that is, primary effusion lymphoma and multicentric Castleman disease. In regions with high HHV-8 seroprevalence ... Read more c b
Intravaginal practices, bacterial vaginosis, and HIV infection in women: individual participant data meta-analysis

Author: Low, Nicola ; Chersich, Matthew F ; Schmidlin, Kurt ; Egger, Matthias ; Francis, Suzanna C ; Van de Wijgert, Janneke H H M ; Hayes, Richard J ; Baeten, Jared M ; Brown, Joelle ; Delany-Moretlwe, Sinead Date: 2011 Pooling of data from 14,874 women in an individual participant data meta-analysis by Nicola Low and colleagues reveals that some intravaginal practices increase the risk of HIV acquisition. Read more c b
Long-term immunologic response to antiretroviral therapy in low-income countries: a collaborative analysis of prospective studies

Author: Nash, Denis ; Katyal, Monica ; Brinkhof, Martin W G ; Keiser, Olivia ; May, Margaret ; Hughes, Rachael ; Dabis, Francois ; Wood, Robin ; Sprinz, Eduardo ; Schechter, Mauro ; Egger, Matthias Date: 2008 Background: Few data are available on the long-term immunologic response to ART in resource-limited settings, where antiretroviral therapy (ART) is being scaled up using a public health approach, with a limited repertoire of drugs. Objectives: ... Read more
Monitoring of antiretroviral therapy and mortality in HIV programmes in Malawi, South Africa and Zambia: mathematical modelling study

Author: Estill, Janne ; Egger, Matthias ; Johnson, Leigh F ; Gsponer, Thomas ; Wandeler, Gilles ; Davies, Mary-Ann ; Boulle, Andrew ; Wood, Robin ; Garone, Daniela ; Stringer, Jeffrey S A Date: 2013 Objectives Mortality in patients starting antiretroviral therapy (ART) is higher in Malawi and Zambia than in South Africa. We examined whether different monitoring of ART (viral load [VL] in South Africa and CD4 count in Malawi and Zambia) ... Read more c b
Mortality of HIV-infected patients starting antiretroviral therapy in sub-Saharan Africa: comparison with HIV-unrelated mortality

Author: Brinkhof, Martin W G ; Boulle, Andrew ; Weigel, Ralf ; Messou, Eugène ; Mathers, Colin ; Orrell, Catherine ; Dabis, François ; Pascoe, Margaret ; Egger, Matthias ; (IeDEA), for the International epidemiological Databases to Evaluate AIDS Date: 2009 Comparing mortality rates between patients starting HIV treatment and the general population in four African countries, Matthias Egger and colleagues find the gap decreases over time, especially with early treatment. Read more c b
Public-health and individual approaches to antiretroviral therapy: township South Africa and Switzerland compared

Author: Keiser, Olivia ; Orrell, Catherine ; Egger, Matthias ; Wood, Robin ; Brinkhof, Martin W G ; Furrer, Hansjakob ; vCutsem, Gilles ; Ledergerber, Bruno ; Boulle, Andrew ; (IeDEA-SA), for the Swiss HIV Cohort Study (SHCS) and the International Epidemiologic Databases Date: 2008 Comparing HIV treatment in Switzerland, where drug selection is individualized, and South Africa, where a programmatic approach is used, Matthias Egger and colleagues find similar virologic outcomes over two years. Read more c b
Retention in care of HIV-infected children from HIV test to start of antiretroviral therapy: systematic review

Author: Mugglin, Catrina ; Wandeler, Gilles ; Estill, Janne ; Egger, Matthias ; Bender, Nicole ; Davies, Mary-Ann ; Keiser, Olivia Date: 2013 BACKGROUND: In adults it is well documented that there are substantial losses to the programme between HIV testing and start of antiretroviral therapy (ART). The magnitude and reasons for loss to follow-up and death between HIV diagnosis and ... Read more c b
Treatment response and mortality among patients starting antiretroviral therapy with and without Kaposi sarcoma: a cohort study

Author: Maskew, Mhairi ; Fox, Matthew P ; Cutsem, Gilles van ; Chu, Kathryn ; MacPhail, Patrick ; Boulle, Andrew ; Egger, Matthias ; Africa, for IeDEA Southern Date: 2013 BACKGROUND: Improved survival among HIV-infected individuals on antiretroviral therapy (ART) has focused attention on AIDS-related cancers including Kaposi sarcoma (KS). However, the effect of KS on response to ART is not well-described in ... Read more c b
When to start antiretroviral therapy in children aged 2-5 years: a collaborative causal modelling analysis of cohort studies from southern Africa

Author: Schomaker, Michael ; Egger, Matthias ; Ndirangu, James ; Phiri, Sam ; Moultrie, Harry ; Technau, Karl ; Cox, Vivian ; Giddy, Janet ; Chimbetete, Cleophas ; Wood, Robin Date: 2013 Michael Schomaker and colleagues estimate the mortality associated with starting ART at different CD4 thresholds among children aged 2-5 years using observational data collected in cohort studies in Southern Africa. Please see later in the ... Read more c b

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Browsing by Author "Egger, Matthias"

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