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Browsing by Author "Bryer, Alan"

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Barriers to acute stroke care at a tertiary hospital in the Western Cape

Author: Matshikiza, Wonga Date: 2019 Background Stroke guidelines recommend treatment of acute stroke as a medical emergency. In many countries prolonged delays occur before patients with acute stroke receive medical attention. Only a small percentage of patients are assessed ... Read more
Clinical and genetic analysis of spinocerebellar ataxia type 7 (SCA7) in Zambian families

Author: Atadzhanov, Masharip ; Smith, Danielle C ; Mwaba, Mwila H ; Siddiqi, Omar K ; Bryer, Alan ; Greenberg, L Jacquie Date: 29 Nov 2017 Background: To date, 43 types of Spinocerebellar Ataxias (SCAs) have been identified. A subset of the SCAs are caused by the pathogenic expansion of a CAG repeat tract within the corresponding gene. Ethnic and geographic differences are evident ... Read more
Community-based care of stroke patients in a rural african setting

Author: Wasserman, Sean ; de Villiers, Linda ; Bryer, Alan Date: 2009 Background: In order to develop a community based-model of stroke care we assessed discharge planning of stroke patients, available resources, and continuity of care between hospital and community in a remote rural setting in South Africa. ... Read more
Early outcomes of thrombolysis for acute ischaemic stroke in a South African tertiary care centre

Author: Wasserman, Sean Date: 2012 Stroke is an important cause of death and disability in sub-Saharan Africa. Recombinant tissue plasminogen activator (tPA) thrombolysis is effective in treating acute ischaemic stroke, but may not be a viable option in developing countries. ... Read more
Poor anticoagulation control in patients taking warfarin at a tertiary and district-level prothrombin clinic in Cape Town, South Africa

Author: Ebrahim, Ismaeel Date: 2018 Background. Warfarin is the most commonly used anticoagulant for both primary and secondary prevention of thromboembolism. For anticoagulation efficacy, the international normalised ratio (INR) needs to be within the therapeutic range for at ... Read more
Pseudotumor cerebri (with special reference to visual loss)

Author: Bryer, Alan Date: 1988 AIMS OF STUDY: 1. To analyse the patients . who have been treated at Groote Schuur Hospital over the last seven years for Pseudotumor Cerebri. 2. To document the clinical features of this group of patients. 3. To determine the visual prognosis ... Read more
Spinocerebellar ataxias

Author: Bryer, Alan Date: 1994 Read more
Stroke outcomes in a socio-economically disadvantaged urban community

Author: De Villiers, Linda ; Badri, Motasim ; Ferreira, Monica ; Bryer, Alan Date: 2011 AIMS: To determine survival, disability and functional outcomes of stroke patients following their discharge from an acute stroke unit in an urban community with limited rehabilitative resources. METHODS: Stroke patients were recruited from ... Read more
The role of the HIV-1 Tat protein in acute stroke: more than just a transactivator of transcription?

Author: McMullen, Kate Elizabeth Date: 2018 Background: Individuals infected with the human immunodeficiency virus (HIV) are at increased risk of developing ischaemic stroke. The reasons for this are multifactorial, but HIV-associated vasculopathy is a potentially important cause. ... Read more
The South African stroke risk in general practice study

Author: Connor, Myles ; Rheeder, Paul ; Bryer, Alan ; Meredith, Megan ; Beukes, Marlene ; Dubb, Asher ; Fritz, Vivian Date: 2005 Background. Incidence of stroke is increasing in sub-Saharan Africa and stroke prevention is an essential component of successful stroke management. General practitioners (GPs) are well placed to manage stroke risk factors. To design appropriate ... Read more
Training 6th year medical students in the use of supportive communication strategies in obtaining a case history from adults with aphasia : preliminary findings

Author: Kahn, Loren Date: 2002 The medical interview is often the ﬁrst point of contact between doctors and patients. For patients who have suffered a stroke, this interaction is often a frustrating attempt to tell the doctor how they are feeling and a struggle on the part ... Read more
The utility of CSF PCR in central nervous system Varicella zoster infection in HIV

Author: Stanley, Alan Michael Date: 2015 Aims: To assess the clinical and cerebrospinal fluid characteristics, and the role of tuberculous meningitis (TBM) as a confounder, in a cohort of HIV positive individuals with positive varicella zoster virus (VZV) positive cerebrospinal fluid ... Read more