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Browsing by Author "Boyles, Tom H"

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Antibiotic stewardship ward rounds and a dedicated prescription chart reduce antibiotic consumption and pharmacy costs without affecting inpatient mortality or re-admission rates

Author: Boyles, Tom H ; Whitelaw, Andrew ; Bamford, Colleen ; Moodley, Mischka ; Bonorchis, Kim ; Morris, Vida ; Rawoot, Naazneen ; Naicker, Vanishree ; Lusakiewicz, Irena ; Black, John Date: 2013 BACKGROUND: Antibiotic consumption is a major driver of bacterial resistance. To address the increasing burden of multi-drug resistant bacterial infections, antibiotic stewardship programmes are promoted worldwide to rationalize antibiotic ... Read more c b
Blood cultures taken from patients attending emergency departments in South Africa are an important antibiotic stewardship tool, which directly influences patient management

Author: Boyles, Tom H ; Davis, Kelly ; Crede, Thomas ; Malan, Jacques ; Mendelson, Marc ; Lesosky, Maia Date: 06 Oct 2015 Abstract Background Febrile illness with suspected blood stream infection (BSI) is a common reason for admission to hospital in Africa and blood cultures are therefore an important investigation. ... Read more
Factors influencing retention in care after starting antiretroviral therapy in a rural South African programme

Author: Boyles, Tom H ; Wilkinson, Lynne S ; Leisegang, Rory ; Maartens, Gary Date: 2011 The prognosis of patients with HIV in Africa has improved with the widespread use of antiretroviral therapy (ART) but these successes are threatened by low rates of long-term retention in care. There are limited data on predictors of retention ... Read more c b
Failure to eradicate Isospora belli diarrhoea despite immune reconstitution in adults with HIV--a case series

Author: Boyles, Tom H ; Black, John ; Meintjes, Graeme ; Mendelson, Marc Date: 2012 Isospora belli causes diarrhoea in patients with AIDS. Most respond to targeted therapy and recommendations are that secondary prophylaxis can be stopped following immune reconstitution with ART. We report eight cases of chronic isosporiasis ... Read more c b
The individualised versus the public health approach to treating Ebola

Author: Boyles, Tom H Date: 2015 The mortality rate for patients with Ebola virus disease (EVD) in West Africa is approximately 65% [1]. There are no published figures for high-resource settings, but media sources and individual case reports suggest it is much lower and ... Read more c b
Knowledge, attitudes and perceptions of antibiotic use and antibiotic resistance among private sector patients and prescribers in South Africa

Author: Farley, Elise Date: 2017 Antibiotic resistance (ABR), alternately referred to as antimicrobial resistance, has been labelled as the next big global health crisis. If current levels of ABR continue along the same trajectories, by 2050 ABR will cost the lives of 10 ... Read more
The prevalence of hepatitis B infection in a rural South African HIV clinic

Author: Boyles, Tom H ; Cohen, Karen Date: 2011 The prevalence of hepatitis B virus (HBV) infection in 1 765 HIVpositive patients in rural Eastern Cape was 7.1%. This is lower than the previously reported rural prevalence and is similar to urban prevalence. Male sex and baseline alanine ... Read more

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Browsing by Author "Boyles, Tom H"

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