Author:Lochan, Harsha; Pillay, Vashini; Bamford, Colleen; Nuttall, James; Eley, BrianDate:06 Dec 2017Background: Bloodstream infection (BSI) in children causes significant morbidity and mortality. There are few studies describing the epidemiology of BSI in South African children. Methods: A retrospective descriptive cohort study was conducted ...Read more
Author:Buys, Heloise; Muloiwa, Rudzani; Bamford, Colleen; Eley, BrianDate:17 Oct 2016Background: Klebsiella pneumoniae (KP) is a significant paediatric bloodstream pathogen in children. There is little data from Africa. In this study we describe the epidemiology of multi-drug resistant Klebsiella pneumoniae bloodstream infection ...Read morecb
Author:Tootla, Hafsah DeepaDate: 2020Introduction: Culture remains the ‘gold standard' for diagnosis of Streptococcus pneumoniae bacteraemia. Time to definitive identification using culture is 24–48 hours, and prior antibiotic therapy, the ability of S. pneumoniae to self-autolyse ...Read more
Author:Khumalo, JermaineDate:2015With conventional methods of diagnosis, substantial overlaps are common due to an absence of the expected CSF findings clearly aligning to bacterial or viral infection. Reduced sensitivity is commonly observed chiefly due to empiric antibiotic ...Read more
Author:Ntuli, Sindile VenessaDate:2018The laboratory diagnosis of fungal infection is complicated, based on the microscopic detection, culture isolation, and detection of serological response. In recent years, there has been an increase in the utilization of molecular diagnostic ...Read more