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Whole Blood Mitochondrial DNA Depletion in Human Immunodeficiency Virus-Infected Children

Author: van der Watt, George Frederick Date: 2010 Background: Nucleoside reverse transcriptase inhibitors (NRTIs) interfere with mitochondrial DNA polymerase gamma causing significant toxic effects, including fatal lactic acidosis. Little is known about mitochondrial DNA (mtDNA) in human ... Read more

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