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Browsing by Author "van der Walt, Eric"

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Adaptive evolution by recombination is not associated with increased mutation rates in Maize streak virus

Author: Monjane, Aderito ; Pande, Daniel ; Lakay, Francisco ; Shepherd, Dionne ; van der Walt, Eric ; Lefeuvre, Pierre ; Lett, Jean-Michel ; Varsani, Arvind ; Rybicki, Edward ; Martin, Darren Date: 2012 BACKGROUND: Single-stranded (ss) DNA viruses in the family Geminiviridae are proving to be very useful in real-time evolution studies. The high mutation rate of geminiviruses and other ssDNA viruses is somewhat mysterious in that their DNA ... Read more c b
Evidence of ancient papillomavirus recombination

Author: Varsani, Arvind ; van der Walt, Eric ; Heath, Livio ; Rybicki, Edward P ; Williamson, Anna Lise ; Martin, Darren P Date: 2006 An open question amongst papillomavirus taxonomists is whether recombination has featured in the evolutionary history of these viruses. Since the onset of the global AIDS epidemic, the question is somewhat less academic, because immune-compromised ... Read more
Experimental observations of rapid Maize streak virus evolution reveal a strand-specific nucleotide substitution bias

Author: van der Walt, Eric ; Martin, Darren ; Varsani, Arvind ; Polston, Jane ; Rybicki, Edward Date: 2008 BACKGROUND: Recent reports have indicated that single-stranded DNA (ssDNA) viruses in the taxonomic families Geminiviridae, Parvoviridae and Anellovirus may be evolving at rates of ~10-4 substitutions per site per year (subs/site/year). These ... Read more c b
Experimental observations of rapid Maize streak virus evolution reveal a strand-specific nucleotide substitution bias

Author: van der Walt, Eric ; Martin, Darren P A ; Varsani, Arvind ; Polston, Jane E ; Rybicki, Edward P Date: 2008 Background: Recent reports have indicated that single-stranded DNA (ssDNA) viruses in the taxonomic families Geminiviridae, Parvoviridae and Anellovirus may be evolving at rates of ~10-4 substitutions per site per year (subs/site/year). These ... Read more c b
Recombination hotspots and host susceptibility modulate the adaptive value of recombination during maize streak virus evolution

Author: Monjane, Aderito ; van der Walt, Eric ; Varsani, Arvind ; Rybicki, Edward ; Martin, Darren Date: 2011 BACKGROUND:Maize streak virus -strain A (MSV-A; Genus Mastrevirus, Family Geminiviridae), the maize-adapted strain of MSV that causes maize streak disease throughout sub-Saharan Africa, probably arose between 100 and 200 years ago via homologous ... Read more c b
Recombination patterns in aphthoviruses mirror those found in other picornaviruses

Author: Heath, Livio ; van der Walt, Eric ; Varsani, Arvind ; Martin, Darren P Date: 2006 Foot-and-mouth disease virus (FMDV) is thought to evolve largely through genetic drift driven by the inherently error-prone nature of its RNA polymerase. There is, however, increasing evidence that recombination is an important mechanism in ... Read more
Viable chimaeric viruses confirm the biological importance of sequence specific maize streak virus movement protein and coat protein interactions

Author: van der Walt, Eric ; Palmer, Kenneth ; Martin, Darren ; Rybicki, Edward Date: 2008 BACKGROUND: A variety of interactions between up to three different movement proteins (MPs), the coat protein (CP) and genomic DNA mediate the inter- and intra-cellular movement of geminiviruses in the genus Begomovirus. Although movement of ... Read more c b

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Browsing by Author "van der Walt, Eric"

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