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Browsing by Author "van Helden, Paul D"

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Determining ancestry proportions in complex admixture scenarios in South Africa using a novel proxy ancestry selection method

Author: Chimusa, Emile R ; Daya, Michelle ; Möller, Marlo ; Ramesar, Raj ; Henn, Brenna M ; van Helden, Paul D ; Mulder, Nicola J ; Hoal, Eileen G Date: 2013 Admixed populations can make an important contribution to the discovery of disease susceptibility genes if the parental populations exhibit substantial variation in susceptibility. Admixture mapping has been used successfully, but is not ... Read more c b
Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages

Author: Phelan, Jody E ; Coll, Francesc ; Bergval, Indra ; Anthony, Richard M ; Warren, Rob ; Sampson, Samantha L ; Gey van Pittius, Nicolaas C ; Glynn, Judith R ; Crampin, Amelia C ; Alves, Adriana ; Bessa, Theolis B ; Campino, Susana ; Dheda, Keertan ; Grandjean, Louis ; Hasan, Rumina ; Hasan, Zahra ; Miranda, Anabela ; Moore, David ; Panaiotov, Stefan ; Perdigao, Joao ; Portugal, Isabel ; Sheen, Patricia ; de Oliveira Sousa, Erivelton ; Streicher, Elizabeth M ; van Helden, Paul D ; Viveiros, Miguel ; Hibberd, Martin L ; Pain, Arnab ; McNerney, Ruth ; Clark, Taane G Date: 29 Feb 2016 Background: Approximately 10 % of the Mycobacterium tuberculosis genome is made up of two families of genes that are poorly characterized due to their high GC content and highly repetitive nature. The PE and PPE families are typified by their ... Read more c b

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