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Browsing by Author "van Diepen, Michiel"

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Advancements in the Growth and Construction of Recombinant Lumpy Skin Disease Virus (LSDV) for Use as a Vaccine Vector

Author: van Diepen, Michiel ; Chapman, Rosamund ; Douglass, Nicola ; Whittle, Leah ; Chineka, Nicole ; Galant, Shireen ; Cotchobos, Christian ; Suzuki, Akiko ; Williamson, Anna-Lise Date: 04 Oct 2021 Attenuated vaccine strains of lumpy skin disease virus (LSDV) have become increasingly popular as recombinant vaccine vectors, to target both LSDV, as well as other pathogens, including human infectious agents. Historically, these vaccine ... Read more c b
Assessment of an LSDV-Vectored Vaccine for Heterologous Prime-Boost Immunizations against HIV

Author: Chapman, Ros ; van Diepen, Michiel ; Douglass, Nicola ; Galant, Shireen ; Jaffer, Mohamed ; Margolin, Emmanuel ; Ximba, Phindile ; Hermanus, Tandile ; Moore, Penny L ; Williamson, Anna-Lise Date: 05 Nov 2021 The modest protective effects of the RV144 HIV-1 vaccine trial have prompted the further exploration of improved poxvirus vector systems that can yield better immune responses and protection. In this study, a recombinant lumpy skin disease ... Read more c b
Characterization of a Novel Chimeric Theileria parva p67 Antigen Which Incorporates into Virus-like Particles and Is Highly Immunogenic in Mice

Author: Whittle, Leah ; Chapman, Ros ; van Diepen, Michiel ; Rybicki, Edward P ; Williamson, Anna-Lise Date: 28 Jan 2022 The current method to protect cattle against East Coast Fever (ECF) involves the use of live <i>Theileria parva</i> sporozoites. Although this provides immunity, using live parasites has many disadvantages, such as contributing to the spread ... Read more c b

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Browsing by Author "van Diepen, Michiel"

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