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Browsing by Author "Zumla, Alimuddin"

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Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis

Author: Pooran, Anil ; Booth, Helen ; Miller, Robert F ; Scott, Geoff ; Badri, Motasim ; Huggett, Jim F ; Rook, Graham ; Zumla, Alimuddin ; Dheda, Keertan Date: 2010 BACKGROUND: Previous health economic studies recommend either a dual screening strategy [tuberculin skin test (TST) followed by interferon-gamma-release assay (IGRA)] or a single one [IGRA only] for latent tuberculosis infection (LTBI), the ... Read more c b
Feasibility and diagnostic utility of antigen-specific interferon-gamma responses for rapid immunodiagnosis of tuberculosis using induced sputum

Author: Cashmore, Tamaryn J ; Peter, Jonathan G ; Van Zyl-Smit, Richard N ; Semple, Patricia L ; Maredza, Alice ; Meldau, Richard ; Zumla, Alimuddin ; Nurse, Barbara ; Dheda, Keertan Date: 2010 BACKGROUND: The diagnosis of smear-negative or sputum-scarce tuberculosis (TB) is problematic as culture takes several weeks and representative biological samples are difficult to obtain. RD-1 antigen-specific interferon-γ release assays ... Read more c b
The pathogen recognition sensor, NOD2, is variably expressed in patients with pulmonary tuberculosis

Author: Lala, Sanjay ; Dheda, Keertan ; Chang, Jung-Su ; Huggett, Jim ; Kim, Louise ; Johnson, Margaret ; Rook, Graham ; Keshav, Satish ; Zumla, Alimuddin Date: 2007 BACKGROUND:NOD2, an intracellular pathogen recognition sensor, modulates innate defences to muropeptides derived from various bacterial species, including Mycobacterium tuberculosis (MTB). Experimentally, NOD2 attenuates two key putative ... Read more c b
Translational research for tuberculosis elimination: priorities, challenges, and actions

Author: Lienhardt, Christian ; Lönnroth, Knut ; Menzies, Dick ; Balasegaram, Manica ; Chakaya, Jeremiah ; Cobelens, Frank ; Cohn, Jennifer ; Denkinger, Claudia M ; Evans, Thomas G ; Källenius, Gunilla ; Kaplan, Gilla ; Kumar, Ajay M V ; Matthiessen, Line ; Mgone, Charles S ; Mizrahi, Valerie ; Mukadi, Ya-diul ; Nguyen, Viet Nhung ; Nordström, Anders ; Sizemore, Christine F ; Spigelman, Melvin ; Squire, S Bertel ; Swaminathan, Soumya ; Helden, Paul D Van ; Zumla, Alimuddin ; Weyer, Karin ; Weil, Diana ; Raviglione, Mario Date: 2016 Christian Lienhardt and colleagues describe the research efforts needed to end the global tuberculosis epidemic by 2035. Read more c b

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Browsing by Author "Zumla, Alimuddin"

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