OpenUCT Home
→
Browsing by Author

Browsing by Author "Workman, Lesley"

Now showing items 1-6 of 6

Adherence to isoniazid prophylaxis among HIV-infected children: a randomized controlled trial comparing two dosing schedules

Author: le Roux, Stanzi ; Cotton, Mark ; Golub, Jonathan ; le Roux, David ; Workman, Lesley ; Zar, Heather Date: 2009 BACKGROUND:Tuberculosis contributes significantly to morbidity and mortality among HIV-infected children in sub-Saharan Africa. Isoniazid prophylaxis can reduce tuberculosis incidence in this population. However, for the treatment to be ... Read more c b
Comparison of mantoux and tine tuberculin skin tests in BCG-vaccinated children investigated for tuberculosis

Author: Pan, Wenli ; Matizirofa, Lyness ; Workman, Lesley ; Hawkridge, Tony ; Hanekom, Willem ; Mahomed, Hassan ; Hussey, Gregory ; Hatherill, Mark Date: 2009 Background: Tuberculin skin tests (TSTs) are long-established screening methods for tuberculosis (TB). We aimed to compare agreement between the intradermal Mantoux and multipuncture percutaneous Tine methods and to quantify risk factors for ... Read more c b
Does helminth treatment reduce the risk of active tuberculosis in a cohort of children from high tuberculosis risk population who have been vaccinated with BCG at birth?

Author: Workman, Lesley Date: 2009 [Background] Research in adults and older children has shown an association between Mycobacterium tuberculosis and helminth infection, with those infected with helminths at greater risk of tuberculosis. This association is believed to be on ... Read more
Human rhinovirus infection in young African children with acute wheezing

Author: Smuts, Heidi ; Workman, Lesley ; Zar, Heather Date: 2011 BACKGROUND:Infections caused by human rhinoviruses (HRVs) are important triggers of wheezing in young children. Wheezy illness has increasingly been recognised as an important cause of morbidity in African children, but there is little ... Read more c b
Making data map-worthy—enhancing routine malaria data to support surveillance and mapping of Plasmodium falciparum anti-malarial resistance in a pre-elimination sub-Saharan African setting: a molecular and spatiotemporal epidemiology study

Author: Kagoro, Frank M. ; Allen, Elizabeth ; Mabuza, Aaron ; Workman, Lesley ; Magagula, Ray ; Kok, Gerdalize ; Davies, Craig ; Malatje, Gillian ; Guérin, Philippe J ; Dhorda, Mehul ; Maude, Richard J ; Raman, Jaishree ; Barnes, Karen I Date: 29 Jun 2022 Background Independent emergence and spread of artemisinin-resistant Plasmodium falciparum malaria have recently been confirmed in Africa, with molecular markers associated with artemisinin resistance increasingly detected. ... Read more
Safety and tolerability of single low-dose primaquine in a low-intensity transmission area in South Africa: an open-label, randomized controlled trial

Author: Raman, Jaishree ; Allen, Elizabeth ; Workman, Lesley ; Mabuza, Aaron ; Swanepoel, Hendrik ; Malatje, Gillian ; Frean, John ; Wiesner, Lubbe ; Barnes, Karen I Date: 24 Jun 2019 Abstract Background To reduce onward falciparum malaria transmission, the World Health Organization recommends adding single low-dose (SLD) primaquine to artemisinin-based combination treatment ... Read more

Now showing items 1-6 of 6

Browse

All of OpenUCT

Browsing by Author "Workman, Lesley"

Browsing by Author "Workman, Lesley"

Browse

All of OpenUCT