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Browsing by Author "Wood, Natasha"

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Experimental evidence indicating that mastreviruses probably did not co-diverge with their hosts

Author: Harkins, Gordon ; Delport, Wayne ; Duffy, Siobain ; Wood, Natasha ; Monjane, Aderito ; Owor, Betty ; Donaldson, Lara ; Saumtally, Salem ; Triton, Guy ; Briddon, Rob ; Shepherd, Dionne ; Rybicki, Edward ; Martin, Darren ; Varsani, Arvind Date: 2009 BACKGROUND:Despite the demonstration that geminiviruses, like many other single stranded DNA viruses, are evolving at rates similar to those of RNA viruses, a recent study has suggested that grass-infecting species in the genus Mastrevirus ... Read more c b
HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC

Author: Wood, Natasha ; Bhattacharya, Tanmoy ; Keele, Brandon F ; Giorgi, Elena ; Liu, Michael ; Gaschen, Brian ; Daniels, Marcus ; Ferrari, Guido ; Haynes, Barton F ; McMichael, Andrew Date: 2009 Author Summary HIV is a rapidly evolving virus, displaying enormous genetic diversity between and even within infected individuals, with implications for vaccine design and drug treatment. Yet, recent research has shown that most new infections ... Read more c b
Refining the HIV-1 glycan shield model: dynamics of a heterogeneous envelope trimer and empirical prediction of glycan processing

Author: Garrard, Clare Date: 2019 The HIV-1 surface protein, Envelope (Env), is covered in asparagine-linked glycans, which interact with the human immune system and are thus important as potential vaccine targets. Laboratory studies have shown that the glycan type and form ... Read more

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