Browsing by Author "Wood, Matthew J A"

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Design of RNAi hairpins for mutation-specific silencing of ataxin-7 and correction of a SCA7 phenotype

Author: Scholefield, Janine ; Greenberg, L Jacquie ; Weinberg, Marc S ; Arbuthnot, Patrick B ; Abdelgany, Amr ; Wood, Matthew J A Date: 2009 Spinocerebellar ataxia type 7 is a polyglutamine disorder caused by an expanded CAG repeat mutation that results in neurodegeneration. Since no treatment exists for this chronic disease, novel therapies such post-transcriptional RNA ... Read more c b

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